Morphology, Volume, and Density Characteristics of the Parotid Glands before and after Chemoradiation Therapy in Patients with Head and Neck Tumors
المؤلفون المشاركون
Costa, André Luiz Ferreira
Braz-Silva, Paulo Henrique
Santos, Wellington Pereira dos
Perez Gomes, João Pedro
Nussi, Amanda Drumstas
João Mauricio Altemani, Amanda Drumstas
Botti Rodrigues dos Santos, Maria Teresa
Hasseus, Bengt
Giglio, Daniel
المصدر
International Journal of Dentistry
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The multimodal approach for patients with head and neck cancer (HNC) includes treatment with chemoradiation therapy (CRT).
A common concern regarding CRT side effects is the occurrence of structural and physiological alterations of the salivary glands due to exposure to ionizing radiation.
The aim of this study is to examine the morphology, volume, and density of the parotid glands before and after CRT in HNC patients.
A total of 49 HNC patients treated exclusively with CRT were included in the study.
Ninety-eight parotid glands were evaluated before and after treatment by using contrast-enhanced computed tomography (CECT).
Shapiro–Wilk test was performed, and the variables (pre-CRT and post-CRT) presented normal distribution.
Pearson’s coefficient was used to assess the correlation between volume and density.
CRT resulted in a significant decrease in the mean volume of the parotid glands (i.e., original volume reduced by 20.5%; P<0.0001).
CRT induced a 30.0% (7 Hounsfield units) increase in density of the right parotid gland and a 24.9% (8 Hounsfield units) increase in density of the left parotid gland (P=0.0198 and P=0.0079, respectively).
Changes in morphology and spatial configuration, increased density, and substantial loss of volume of the parotid glands were observed after CRT.
There was also a difference in density (P=0.003) in the right-side parotid glands in comparison between xerostomic and nonxerostomic groups of patients.
These facts lead to the need for a personalized CRT planning in order to minimize oral complications related to the treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Santos, Wellington Pereira dos& Perez Gomes, João Pedro& Nussi, Amanda Drumstas& João Mauricio Altemani, Amanda Drumstas& Botti Rodrigues dos Santos, Maria Teresa& Hasseus, Bengt…[et al.]. 2020. Morphology, Volume, and Density Characteristics of the Parotid Glands before and after Chemoradiation Therapy in Patients with Head and Neck Tumors. International Journal of Dentistry،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1169643
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Santos, Wellington Pereira dos…[et al.]. Morphology, Volume, and Density Characteristics of the Parotid Glands before and after Chemoradiation Therapy in Patients with Head and Neck Tumors. International Journal of Dentistry No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1169643
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Santos, Wellington Pereira dos& Perez Gomes, João Pedro& Nussi, Amanda Drumstas& João Mauricio Altemani, Amanda Drumstas& Botti Rodrigues dos Santos, Maria Teresa& Hasseus, Bengt…[et al.]. Morphology, Volume, and Density Characteristics of the Parotid Glands before and after Chemoradiation Therapy in Patients with Head and Neck Tumors. International Journal of Dentistry. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1169643
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1169643
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر