Treatment Outcome of Carcinoma Vulva Ten-Year Experience from a Tertiary Cancer Centre in South India

الملخص EN

Background.

Carcinoma vulva is a rare disease accounting for 1.3% of all gynaecological malignancies.

The present study is a 10-year retrospective review of our experience of the surgical options, morbidity, failure pattern, and survival for invasive carcinoma vulva.

Materials and Methods.

Retrospective analysis of case records of 39 patients who underwent surgery for invasive vulval cancer between 2004 and 2013 in the Department of Surgical Oncology at the Government Royapettah Hospital, Chennai.

Results.

The median age was 55 years.

Radical vulvectomy was the preferred surgery.

31 patients underwent lymphadenectomy.

Seroma formation and groin skin necrosis were the most common postoperative complications.

With a median follow-up of 32 months, 8 patients (20.5%) developed recurrence (systemic = 1, regional = 4, and local = 3).

The estimated 5-year disease-free survival (DFS) was 65.4% and the overall survival (OS) was 85.1%.

On univariate analysis, stage and lymph node involvement significantly affected OS.

Nodal involvement with extracapsular spread (ECS) significantly affected both DFS and OS.

Conclusion.

The treatment of carcinoma vulva should be individualized with multidisciplinary cooperation.

The paucity of data, especially from India, necessitates the need for more studies, preferably multicentric, keeping in mind the low prevalence.