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Efficacy and Safety of Daikenchuto for Constipation and Dose-Dependent Differences in Clinical Effects
المؤلفون المشاركون
Hirose, Tatsuya
Shinoda, Yasutaka
Kuroda, Ayaka
Yoshida, Aya
Mitsuoka, Machiko
Mori, Kouki
Kawachi, Yuki
Moriya, Akihiro
Tanaka, Kouji
Takeda, Atsuko
Yoshimura, Tomoaki
Sugiyama, Tadashi
المصدر
International Journal of Chronic Diseases
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-05
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Daikenchuto (DKT) is a Kampo medicine used for the treatment of constipation.
In this study, we evaluated the effectiveness of DKT against constipation.
Patients and Methods.
Thirty-three patients administered DKT for constipation were selected and divided into low-dose (7.5 g DKT; n=22) and high-dose (15 g DKT; n=11) groups.
We retrospectively evaluated weekly defaecation frequency, side effects, and clinical laboratory data.
Results.
Median defaecation frequencies after DKT administration (5, 5.5, 5, and 8 for the first, second, third, and fourth weeks, resp.) were significantly higher than that before DKT administration (2) in all 33 cases (P<0.01).
One case (3%) of watery stool, one case of loose stools (3%), and no cases of abdominal pain (0%) were observed.
Median defaecation frequencies in the high-dose group (7 and 9) were significantly higher than those in the low-dose group (4 and 3) in the first (P=0.0133) and second (P=0.0101) weeks, respectively.
There was no significant change in clinical laboratory values.
Conclusion.
We suggest that DKT increases defaecation frequency and is safe for treating constipation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hirose, Tatsuya& Shinoda, Yasutaka& Kuroda, Ayaka& Yoshida, Aya& Mitsuoka, Machiko& Mori, Kouki…[et al.]. 2018. Efficacy and Safety of Daikenchuto for Constipation and Dose-Dependent Differences in Clinical Effects. International Journal of Chronic Diseases،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1170021
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hirose, Tatsuya…[et al.]. Efficacy and Safety of Daikenchuto for Constipation and Dose-Dependent Differences in Clinical Effects. International Journal of Chronic Diseases No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1170021
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hirose, Tatsuya& Shinoda, Yasutaka& Kuroda, Ayaka& Yoshida, Aya& Mitsuoka, Machiko& Mori, Kouki…[et al.]. Efficacy and Safety of Daikenchuto for Constipation and Dose-Dependent Differences in Clinical Effects. International Journal of Chronic Diseases. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1170021
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1170021
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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