Assessment of Toxicity and Therapeutic Effects of Goose Bone in a Rat Model
المؤلفون المشاركون
Aminul Islam, Md.
Khalil, Md. Ibrahim
Hossen, Md. Sakib
Ali, Md. Yousuf
Kabir, Alamgir
Khandker, Shahad Saif
Hossan, Tareq
Shakil, Md. Salman
Hasan, Md. Ashraful
Gan, Siew Hua
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-29
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Goose bone is traditionally used in the treatment of many ailments including in bone fracture.
The aim of the present study was to evaluate the subacute toxicity of goose bone in a rat model by investigating some hematological and biochemical parameters in rats.
Subsequently, a histopathological study was performed to confirm the presence of pathological lesions in the rat’s vital organs including the liver, kidney, heart, brain, pancreas, lung, spleen, and stomach.
Adult Wistar rats were divided into four groups (n = 8) and were orally administrated with three doses (30, 60, and 120 mg/kg) of goose bone once daily for 21 days as compared to control animals (received only drinking water).
Goose bone did not cause any significant changes on body weight, relative organ weight, and percentage water content at any of the administered doses.
There were also no significant alterations in hematological parameters seen.
All three doses administered significantly reduced the triglyceride levels as well as the atherogenic index of plasma (AIP).
Animals treated with 120 mg/kg doses had significantly reduced alkaline phosphatase (ALP) activity as compared to the control group.
There was no significant alteration on other serum biochemical parameters seen.
Additionally, histopathological findings confirmed that there was no inflammatory, necrotic, or other toxicological feature seen for all three doses.
It is concluded that goose bone is nontoxic and is safe for consumption besides having the potential to be investigated for the treatment of high triglycerides or liver-related disorder.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ali, Md. Yousuf& Kabir, Alamgir& Khandker, Shahad Saif& Hossan, Tareq& Shakil, Md. Salman& Aminul Islam, Md.…[et al.]. 2019. Assessment of Toxicity and Therapeutic Effects of Goose Bone in a Rat Model. Journal of Chemistry،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1170666
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ali, Md. Yousuf…[et al.]. Assessment of Toxicity and Therapeutic Effects of Goose Bone in a Rat Model. Journal of Chemistry No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1170666
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ali, Md. Yousuf& Kabir, Alamgir& Khandker, Shahad Saif& Hossan, Tareq& Shakil, Md. Salman& Aminul Islam, Md.…[et al.]. Assessment of Toxicity and Therapeutic Effects of Goose Bone in a Rat Model. Journal of Chemistry. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1170666
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1170666
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر