Fecal Microbiota Transplantation for Clostridioides Difficile Infection in Patients with Chronic Liver Disease
المؤلفون المشاركون
Ramesh, Mayur S.
Meighani, Alireza
Alimirah, Maryam
Salgia, Reena
المصدر
International Journal of Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Fecal microbiota transplantation (FMT) is a well-established therapeutic option for patients with antibiotic resistant Clostridioides difficile infection (CDI).
However, the efficacy of FMT in patients with chronic liver disease remains elusive.
Aims.
We studied the effect of FMT on chronic liver disease (CLD) patients with CDI at our tertiary medical center.
Methods.
A cohort of all patients who received FMT from December 2012 to May 2014 for refractory or recurrent CDI was identified.
Patients were monitored for a year after FMT.
Descriptive analysis was conducted to compare the effect of FMT in patients with and without CLD.
Results.
A total of 201 patients with CDI received FMT, 14 of which had a history of CLD.
Nine of these patients exhibited cirrhosis of the liver with a mean Child-Turcotte-Pugh score of 8.
CDI development in these patients was associated with recent exposure to antibiotics and was observed to be significantly different between both groups (17% of CLD patients vs.
58% in the general cohort, p=0.01).
Four patients with CLD received >1 FMT, of which 2 did not respond to treatment.
There was no significant difference between patients with liver disease and the rest of the cohort with regard to FMT response (12/14 (87%) vs.
164/187 (88%), p=0.68).
Conclusion.
FMT is a safe and effective therapy against CDI for patients with CLD and cirrhosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Meighani, Alireza& Alimirah, Maryam& Ramesh, Mayur S.& Salgia, Reena. 2020. Fecal Microbiota Transplantation for Clostridioides Difficile Infection in Patients with Chronic Liver Disease. International Journal of Hepatology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1171430
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Meighani, Alireza…[et al.]. Fecal Microbiota Transplantation for Clostridioides Difficile Infection in Patients with Chronic Liver Disease. International Journal of Hepatology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1171430
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Meighani, Alireza& Alimirah, Maryam& Ramesh, Mayur S.& Salgia, Reena. Fecal Microbiota Transplantation for Clostridioides Difficile Infection in Patients with Chronic Liver Disease. International Journal of Hepatology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1171430
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1171430
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر