Pericardial Fat Relates to Disturbances of Glucose Metabolism in Women with the Polycystic Ovary Syndrome, but Not in Healthy Control Subjects
المؤلفون المشاركون
Leutner, Michael
Göbl, Christian
Bozkurt, Latife
Wolf, Peter
Maruszczak, Katharina
Steinbrecher, Helmut
Just-Kukurova, Ivica
Ott, Johannes
Egarter, Christian
Trattnig, Siegfried
Kautzky-Willer, Alexandra
المصدر
International Journal of Endocrinology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
The objective of the present study is to investigate the relationship of cardiac fat depots with disturbances of the carbohydrate metabolism in women with PCOS.
Methods.
An oral glucose tolerance test (OGTT) was realized, and metabolic parameters were collected in 48 women with PCOS and in 20 controls.
Intramyocardial fat (MYCL) and pericardial fat (PERI) were measured using 1H-magnetic resonance spectroscopy and imaging.
Results.
Only in PCOS women, PERI was positively and independently related to parameters of glucose metabolism (HbA1c: p=0.001, fasting plasma glucose: p<0.001, stimulated glucose at 30 and 60 minutes in the OGTT).
Thus, the disposition index, insulin sensitivity, and adiponectin also declined with the increase of PERI in women with PCOS; however, these results were not independent of BMI and age.
In addition, PERI was positively related to atherogenic lipid profiles, BMI, waist circumference, CRP, and liver fat in women with PCOS.
A negative relation of PERI with triglycerides and a positive relation with BMI and waist circumference could be observed in the controls.
No relationship of MYCL with diabetes-specific parameters could be found in the study population.
Conclusion.
PERI is related to metabolic disturbances in women with PCOS, but not in metabolically healthy lean subjects.
This clinical trial was registered at ClinicalTrials.gov and has the registration number NCT03204461.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Leutner, Michael& Göbl, Christian& Wolf, Peter& Maruszczak, Katharina& Bozkurt, Latife& Steinbrecher, Helmut…[et al.]. 2018. Pericardial Fat Relates to Disturbances of Glucose Metabolism in Women with the Polycystic Ovary Syndrome, but Not in Healthy Control Subjects. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1171533
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Leutner, Michael…[et al.]. Pericardial Fat Relates to Disturbances of Glucose Metabolism in Women with the Polycystic Ovary Syndrome, but Not in Healthy Control Subjects. International Journal of Endocrinology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1171533
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Leutner, Michael& Göbl, Christian& Wolf, Peter& Maruszczak, Katharina& Bozkurt, Latife& Steinbrecher, Helmut…[et al.]. Pericardial Fat Relates to Disturbances of Glucose Metabolism in Women with the Polycystic Ovary Syndrome, but Not in Healthy Control Subjects. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1171533
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1171533
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر