Heart in Acromegaly: The Echocardiographic Characteristics of Patients Diagnosed with Acromegaly in Various Stages of the Disease
المؤلفون المشاركون
Zgliczyński, Wojciech
Konwicka, Aleksandra
Dąbrowski, Marek
Popielarz-Grygalewicz, Agata
Gąsior, Jakub S.
Grygalewicz, Paweł
Stelmachowska-Banaś, Maria
المصدر
International Journal of Endocrinology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
To determine whether the echocardiographic presentation allows for diagnosis of acromegalic cardiomyopathy.
140 patients with acromegaly underwent echocardiography as part of routine diagnostics.
The results were compared with the control group comprising of 52 age- and sex-matched healthy volunteers.
Patients with acromegaly presented with higher BMI, prevalence of arterial hypertension, and glucose metabolism disorders (i.e., diabetes and/or prediabetes).
In patients with acromegaly, the following findings were detected: increased left atrial volume index, increased interventricular septum thickness, increased posterior wall thickness, and increased left ventricular mass index, accompanied by reduced diastolic function measured by the following parameters: E’med., E/E’, and E/A.
Additionally, they presented with abnormal right ventricular systolic pressure.
All patients had normal systolic function measured by ejection fraction.
However, the values of global longitudinal strain were slightly lower in patients than in the control group; the difference was statistically significant.
There were no statistically significant differences in the size of the right and left ventricle, thickness of the right ventricular free wall, and indexed diameter of the ascending aorta between patients with acromegaly and healthy volunteers.
None of 140 patients presented systolic dysfunction, which is the last phase of the so-called acromegalic cardiomyopathy.
Some abnormal echocardiographic parameters found in acromegalic patients may be caused by concomitant diseases and not elevated levels of GH or IGF-1 alone.
The potential role of demographic parameters like age, sex, and/or BMI requires further research.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Popielarz-Grygalewicz, Agata& Gąsior, Jakub S.& Konwicka, Aleksandra& Grygalewicz, Paweł& Stelmachowska-Banaś, Maria& Zgliczyński, Wojciech…[et al.]. 2018. Heart in Acromegaly: The Echocardiographic Characteristics of Patients Diagnosed with Acromegaly in Various Stages of the Disease. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171872
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Popielarz-Grygalewicz, Agata…[et al.]. Heart in Acromegaly: The Echocardiographic Characteristics of Patients Diagnosed with Acromegaly in Various Stages of the Disease. International Journal of Endocrinology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1171872
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Popielarz-Grygalewicz, Agata& Gąsior, Jakub S.& Konwicka, Aleksandra& Grygalewicz, Paweł& Stelmachowska-Banaś, Maria& Zgliczyński, Wojciech…[et al.]. Heart in Acromegaly: The Echocardiographic Characteristics of Patients Diagnosed with Acromegaly in Various Stages of the Disease. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1171872
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1171872
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر