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Risk of Microvascular Complications and Macrovascular Risk Factors in Early-Onset Type 1 Diabetes after at Least 10 Years Duration: An Analysis of Three Population-Based Cross-Sectional Surveys in Germany between 2009 and 2016
المؤلفون المشاركون
Rosenbauer, J.
Holl, R. W.
Tönnies, Thaddäus
Stahl-Pehe, Anna
Baechle, Christina
Castillo, Katty
Kuss, Oliver
Yossa, Rhuphine
Lindner, Lena M. E.
المصدر
International Journal of Endocrinology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-01
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Aims.
To estimate the risk of microvascular complications and macrovascular risk factors among persons with early-onset (diagnosed at ages 0 to <5 years) and long-duration type 1 diabetes and determine temporal trends and associations with potential predictors.
Methods.
We conducted three population-based cross-sectional surveys in Germany (N=1789) to obtain information on exposures and five outcomes (retinopathy, nephropathy, dyslipidemia, hypertension, and a composite endpoint combining all four outcomes).
For each outcome, log-binomial spline regression was applied to estimate the risk and dose-response relationship with diabetes duration and exposures.
Results.
The risk for microvascular complications increased after 14 years since diabetes diagnosis whereas dyslipidemia and hypertension were already prevalent at 10 years.
The 15-year risk (95% confidence interval) of the composite endpoint for female and male patients was 22.9% (18.8%–27.9%) and 19.2% (15.5%–23.8%), respectively.
Temporal trends suggested a decreasing risk between 2009 and 2016.
Glycemic control, lifestyle-related factors, and SES, but not health care-related factors, were associated with the risk of the composite endpoint.
Conclusions.
In early-onset type 1 diabetes, there exists a considerable risk of complications and comorbidities already in young ages.
Future research should focus on prevention of diabetic complications in young patients and clarification of pathways of the associations found.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tönnies, Thaddäus& Stahl-Pehe, Anna& Baechle, Christina& Castillo, Katty& Kuss, Oliver& Yossa, Rhuphine…[et al.]. 2018. Risk of Microvascular Complications and Macrovascular Risk Factors in Early-Onset Type 1 Diabetes after at Least 10 Years Duration: An Analysis of Three Population-Based Cross-Sectional Surveys in Germany between 2009 and 2016. International Journal of Endocrinology،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1172028
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tönnies, Thaddäus…[et al.]. Risk of Microvascular Complications and Macrovascular Risk Factors in Early-Onset Type 1 Diabetes after at Least 10 Years Duration: An Analysis of Three Population-Based Cross-Sectional Surveys in Germany between 2009 and 2016. International Journal of Endocrinology No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1172028
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tönnies, Thaddäus& Stahl-Pehe, Anna& Baechle, Christina& Castillo, Katty& Kuss, Oliver& Yossa, Rhuphine…[et al.]. Risk of Microvascular Complications and Macrovascular Risk Factors in Early-Onset Type 1 Diabetes after at Least 10 Years Duration: An Analysis of Three Population-Based Cross-Sectional Surveys in Germany between 2009 and 2016. International Journal of Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1172028
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172028
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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