Prevalence of Asymptomatic Bacteriuria and Antibiotic Susceptibility Patterns of Bacterial Isolates among Cancer Patients and Healthy Blood Donors at the University of Gondar Specialized Hospital
المؤلفون المشاركون
Tigabu, Abiye
Ferede, Worku
Belay, Gizeaddis
Gelaw, Baye
المصدر
International Journal of Microbiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-17
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Urinary tract infections are the common types of infections in the community and health care settings.
Despite the widespread availability of antibiotics, urinary tract infection remains a worldwide therapeutic problem.
It is a continuous and significant problem in cancer patients.
Methods.
A hospital-based comparative cross-sectional study was conducted on 240 study participants from January to June 2019.
Sociodemographic data were collected by a predesigned questionnaire and midstream urine samples collected using simple random sampling technique by using clean, sterile plastic cups and then inoculated onto CLED agar plates and incubated at 37°C for 24 hours.
Urine culture was considered significant bacteriuria when colony forming units ≥105/mL of voided urine and a single pure colony suspended in nutrient broth and then subcultured onto a blood agar plate and MacConkey agar plate, incubated at 37°C for 24 hours for identification.
Identification was done by using standard microbiological methods.
Modified Kirby–Bauer disk diffusion technique was applied for antimicrobial susceptibility testing in accordance with CLSI 2018 criteria.
Data were entered, cleared, and checked using Epi Info version 7 and exported to SPSS version 20 for analysis.
The results were displayed using tables and figures.
p value <0.05 at 95% CI was considered as statistically significant.
Results.
The overall prevalence of asymptomatic bacteriuria in cancer patients was 23.3% while 6.7% in apparently healthy blood donors.
E.
coli (32.1%) was the commonest isolated uropathogenic bacteria followed by Klebsiella species (25.0%), S.
aureus (21.4%), Enterococcus species (10.7%), Serratia species (7.1%), and Enterobacter aerogenes (3.6%) in cancer patients.
In apparently healthy blood donors, E.
coli, Klebsiella species, and S.
aureus were isolated from 75%, 12.5%, and 12.5%, respectively.
Most Gram-negative bacteria were more sensitive to ceftazidime, cefoxitin, nalidixic acid, nitrofurantoin, norfloxacin, ciprofloxacin, and tobramycin, whereas highly resistant to ampicillin, penicillin, tetracycline, and ceftazidime.
S.
aureus isolates were 100% susceptible to nitrofurantoin.
Conclusions.
This study showed a high prevalence of asymptomatic bacteriuria among cancer patients (23.3%) compared to apparently healthy blood donors (6.7%).
E.
coli was isolated predominately.
Nitrofurantoin and ciprofloxacin should be used to treat asymptomatic bacteriuria in the study area.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tigabu, Abiye& Ferede, Worku& Belay, Gizeaddis& Gelaw, Baye. 2020. Prevalence of Asymptomatic Bacteriuria and Antibiotic Susceptibility Patterns of Bacterial Isolates among Cancer Patients and Healthy Blood Donors at the University of Gondar Specialized Hospital. International Journal of Microbiology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1172069
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tigabu, Abiye…[et al.]. Prevalence of Asymptomatic Bacteriuria and Antibiotic Susceptibility Patterns of Bacterial Isolates among Cancer Patients and Healthy Blood Donors at the University of Gondar Specialized Hospital. International Journal of Microbiology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1172069
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tigabu, Abiye& Ferede, Worku& Belay, Gizeaddis& Gelaw, Baye. Prevalence of Asymptomatic Bacteriuria and Antibiotic Susceptibility Patterns of Bacterial Isolates among Cancer Patients and Healthy Blood Donors at the University of Gondar Specialized Hospital. International Journal of Microbiology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1172069
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172069
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر