Molecular Encapsulation of Herbicide Terbuthylazine in Native and Modified β-Cyclodextrin
المؤلفون المشاركون
Garrido, E. Manuela
Rodrigues, Daniela
Milhazes, Nuno
Borges, Fernanda
Garrido, Jorge
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-09
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The herbicide terbuthylazine (TBA) is widely used for preemergence or postemergence control of many grass and broadleaf weeds and has, besides other issues, a poor aqueous solubility profile that results in reduced bioavailability.
Cyclodextrins and modified cyclodextrins were considered, among other substances, appropriate agents for improving pesticide water solubility.
Therefore, the inclusion complex formation of terbuthylazine with β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) was studied to attain its aqueous solubility enhancement.
Their characterization was accomplished with different analytical techniques, namely, by UV-Vis, DSC, FTIR, and 1H NMR.
From the analysis of the complexation performance of the herbicide it was concluded that the interaction of terbuthylazine with CDs leads to the formation of inclusion complexes with a stoichiometry of 1 : 1.
The association constants of the TBA/β-CD and TBA/HP-β-CD complexes were determined by UV.
The mean values obtained for the stability constants are 460.4 ± 26.5 and 532.1 ± 27.6 to TBA/β-CD and TBA/HP-β-CD, respectively.
1H NMR data corroborate the formation of the TBA/β-CD and TBA/HP-β-CD complexes synthesized by the kneading method.
A formulation incorporating TBA cyclodextrin complexes might lead to an improvement in terbuthylazine bioavailability.
The development of TBA-CD formulations may be interesting since it would enable, through their inclusion into the hydrophobic cavity of CDs, enhancement of solubility, bioavailability, and stability of the herbicide.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Garrido, E. Manuela& Rodrigues, Daniela& Milhazes, Nuno& Borges, Fernanda& Garrido, Jorge. 2017. Molecular Encapsulation of Herbicide Terbuthylazine in Native and Modified β-Cyclodextrin. Journal of Chemistry،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1172385
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Garrido, E. Manuela…[et al.]. Molecular Encapsulation of Herbicide Terbuthylazine in Native and Modified β-Cyclodextrin. Journal of Chemistry No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1172385
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Garrido, E. Manuela& Rodrigues, Daniela& Milhazes, Nuno& Borges, Fernanda& Garrido, Jorge. Molecular Encapsulation of Herbicide Terbuthylazine in Native and Modified β-Cyclodextrin. Journal of Chemistry. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1172385
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172385
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر