Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts
المؤلفون المشاركون
Nofiani, Risa
Weisberg, Alexandra J.
Tsunoda, Takeshi
Panjaitan, Ruqiah Ganda Putri
Brilliantoro, Ridho
Chang, Jeff H.
Philmus, Benjamin
Mahmud, Taifo
المصدر
International Journal of Microbiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-29
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Indonesian marine environments are known to house diverse organisms.
However, the potential for bacteria from these environments as a source of antibacterial agents has not been widely studied.
This study aims to explore the antibacterial potential of secondary metabolites produced by bacterial symbionts from sponges and corals collected in the Indonesian waters.
Extracts of 12 bacterial isolates from sponges or corals were prepared by cultivating the bacteria under a number of different media conditions and using agar well diffusion assays to test for antibacterial activity.
In addition, the morphology, physiology, and biochemical characteristics and 16S rRNA sequence of each isolate were used to determine their taxonomic classification.
All tested bacterial isolates were able to produce secondary metabolites with various levels of antibacterial activity depending on medium composition and culture conditions.
Two of the bacteria (RS3 and RC4) showed strong antibacterial activities against both Gram-negative and Gram-positive bacteria.
A number of isolates (RS1, RS3, and RC2) were co-cultured with mycolic acid-containing bacteria, Mycobacterium smegmatis or Rhodococcus sp.
However, no improvements in their antibacterial activity were observed.
All of the 12 bacteria tested were identified as Streptomyces spp.
LC-MS analysis of EtOAc extracts from the most active strains RS3 and RC4 revealed the presence of a number of dactinomycin analogues and potentially new secondary metabolites.
Symbiotic Streptomyces spp.
from sponges and corals of the Indonesian marine environments have great potential as a source of broad-spectrum antibacterial agents.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nofiani, Risa& Weisberg, Alexandra J.& Tsunoda, Takeshi& Panjaitan, Ruqiah Ganda Putri& Brilliantoro, Ridho& Chang, Jeff H.…[et al.]. 2020. Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts. International Journal of Microbiology،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1172540
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nofiani, Risa…[et al.]. Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts. International Journal of Microbiology No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1172540
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nofiani, Risa& Weisberg, Alexandra J.& Tsunoda, Takeshi& Panjaitan, Ruqiah Ganda Putri& Brilliantoro, Ridho& Chang, Jeff H.…[et al.]. Antibacterial Potential of Secondary Metabolites from Indonesian Marine Bacterial Symbionts. International Journal of Microbiology. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1172540
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172540
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر