The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease
المؤلفون المشاركون
Lu, Zhenzhen
Zhong, Yifei
Liu, Wangyi
Xiang, Ling
Deng, Yueyi
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-08-25
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Diabetic kidney disease (DKD) is the most common microvascular complication of diabetes and is one of the main causes of end-stage renal disease (ESRD) in many countries.
The pathological features of DKD are the hypertrophy of mesangial cells, apoptosis of podocytes, glomerular basement membrane (GBM) thickening, accumulation of extracellular matrix (ECM), glomerular sclerosis, and tubulointerstitial fibrosis.
The etiology of DKD is very complicated and many factors are involved, such as genetic factors, hyperglycemia, hypertension, hyperlipidemia, abnormalities of renal hemodynamics, and metabolism of vasoactive substances.
Although some achievements have been made in the exploration of the pathogenesis of DKD, the currently available clinical treatment methods are still not completely effective in preventing the progress of DKD to ESRD.
CHM composed of natural products has traditionally been used for symptom relief, which may offer new insights into therapeutic development of DKD.
We will summarize the progress of Chinese herbal medicine (CHM) in the treatment of DKD from two aspects.
In clinical trials, the Chinese herbal formulas were efficacy and safety confirmed by the randomized controlled trials.
In terms of experimental research, studies provided evidence for the efficacy of CHM from the perspectives of balancing metabolic disorders, reducing inflammatory response and oxidative stress, antifibrosis, protecting renal innate cells, and regulating microRNA and metabolism.
CHM consisting of different ingredients may play a role in synergistic interactions and multiple target points in the treatment of DKD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Zhenzhen& Zhong, Yifei& Liu, Wangyi& Xiang, Ling& Deng, Yueyi. 2019. The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1172849
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Zhenzhen…[et al.]. The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease. Journal of Diabetes Research No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1172849
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Zhenzhen& Zhong, Yifei& Liu, Wangyi& Xiang, Ling& Deng, Yueyi. The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1172849
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172849
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر