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Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter
المؤلفون المشاركون
Keane, Kevin N.
Cruzat, Vinicius F.
Heck, Thiago Gomes
Kostrycki, Iberê Machado
Wildner, Guilherme
Donato, Yohanna Hannah
dos Santos, Analú Bender
Beber, Lílian Corrêa Costa
Frizzo, Matias Nunes
Ludwig, Mirna Stela
Rhoden, Cláudia Ramos
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-06
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Obesity, air pollution, and exercise induce alterations in the heat shock response (HSR), in both intracellular 70 kDa heat shock proteins (iHSP70) and the plasmatic extracellular form (eHSP72).
Extra-to-intracellular HSP70 ratio (H-index = eHSP70/iHSP70 ratio) represents a candidate biomarker of subclinical health status.
This study investigated the effects of moderate- and high-intensity exercise in the HSR and oxidative stress parameters, in obese mice exposed to fine particulate matter (PM2.5).
Thirty-day-old male isogenic B6129F2/J mice were maintained for 16 weeks on standard chow or high-fat diet (HFD).
Then, mice were exposed to either saline or 50 μg of PM2.5 by intranasal instillation and subsequently maintained at rest or subjected to moderate- or high-intensity swimming exercise.
HFD mice exhibited high adiposity and glucose intolerance at week 16th.
HFD mice submitted to moderate- or high-intensity exercise were not able to complete the exercise session and showed lower levels of eHSP70 and H-index, when compared to controls.
PM2.5 exposure modified the glycaemic response to exercise and modified hematological responses in HFD mice.
Our study suggests that obesity is a critical health condition for exercise prescription under PM2.5 exposure.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kostrycki, Iberê Machado& Wildner, Guilherme& Donato, Yohanna Hannah& dos Santos, Analú Bender& Beber, Lílian Corrêa Costa& Frizzo, Matias Nunes…[et al.]. 2019. Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1172972
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kostrycki, Iberê Machado…[et al.]. Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter. Journal of Diabetes Research No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1172972
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kostrycki, Iberê Machado& Wildner, Guilherme& Donato, Yohanna Hannah& dos Santos, Analú Bender& Beber, Lílian Corrêa Costa& Frizzo, Matias Nunes…[et al.]. Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1172972
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1172972
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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