A Seven-Year Retrospective Study on the Surveillance of Hepatitis B in Laos
المؤلفون المشاركون
Paboriboune, Phimpha
Vial, Thomas
Chassagne, François
Sitbounlang, Philavanh
Soundala, Sengaloun
Bertani, Stéphane
Sengmanothong, Davone
Babin, Francois-Xavier
Steenkeste, Nicolas
Dény, Paul
Pineau, Pascal
Deharo, Eric
المصدر
International Journal of Hepatology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-01
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Objective.
Lao PDR is one of the most highly endemic countries for hepatitis B in Asia and the second country for liver cancer incidence.
Therefore, the follow-up of infected individuals through predictive serological markers is of utmost importance to monitor the progression of the pathology and take the decision on treatment.
Methods.
A retrospective-descriptive cohort study was conducted on 3,857 HBV-infected patients.
Information about infection status (viral load, VL), liver function (aminotransferases), and treatments was recorded.
Results.
M/F sex ratio was 1.77 for a median age of 37.
Patients under 37 displayed higher VL than older ones and men had higher VL than women.
Initial VL ranged from <50 IU/mL to 2.5 1013 IU/mL.
Median aminotransferase values were 45.5 U/L for ALAT and 44 U/L for ASAT, ranging from <8 to >2,000 U/L.
Men had higher aminotransferase than women.
Globally 20% of patients received treatment (mainly immunostimulant and reverse-transcriptase inhibitors); 11% had high levels of VL and liver enzymes, but only 2% of them were treated.
Conclusion.
Public health decisions should be taken urgently to rationalise vaccination and provide fair access to early diagnosis and treatment; otherwise the burden of HBV-associated diseases will be overwhelming for Laos in the near future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Paboriboune, Phimpha& Vial, Thomas& Chassagne, François& Sitbounlang, Philavanh& Soundala, Sengaloun& Bertani, Stéphane…[et al.]. 2018. A Seven-Year Retrospective Study on the Surveillance of Hepatitis B in Laos. International Journal of Hepatology،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1173074
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Paboriboune, Phimpha…[et al.]. A Seven-Year Retrospective Study on the Surveillance of Hepatitis B in Laos. International Journal of Hepatology No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1173074
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Paboriboune, Phimpha& Vial, Thomas& Chassagne, François& Sitbounlang, Philavanh& Soundala, Sengaloun& Bertani, Stéphane…[et al.]. A Seven-Year Retrospective Study on the Surveillance of Hepatitis B in Laos. International Journal of Hepatology. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1173074
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173074
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر