Impact of Hypoglycemia on Health-Related Quality of Life among Type 2 Diabetes: A Cross-Sectional Study in Thailand
المؤلفون المشاركون
Ongphiphadhanakul, Boonsong
Satirapoj, Bancha
Pratipanawatr, Thongchai
Suwanwalaikorn, Sompongse
Nitiyanant, Wannee
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases.
Patients are generally advised lifestyle changes with antihyperglycemic agents prescribed.
The major drawback of prescribing antihyperglycemic agents is the risk of hypoglycemia which subsequently impacts on health-related quality of life (HRQoL).
This study is aimed at examining association between previous history of hypoglycemia and HRQoL.
The study was a multicenter cross-sectional study, conducted from February 2013 to March 2015 at 5 tertiary care hospitals in Thailand (Srinagarind, Phramongkutklao, Ramathibodi, King Chulalongkorn Memorial, and Siriraj hospitals).
The study population were males or females diagnosed with type 2 DM according to ADA criteria, 30 years of age or older, who had been treated with sulfonylurea (SU) monotherapy or SU and metformin combination for at least 6 months.
Prespecified medical factors were extracted from medical records 12 months prior to patients’ enrolment.
The experience of hypoglycemia questionnaire was used to collect and measure severity of hypoglycemia experienced during the previous 6 months.
HRQoL was assessed using the 3-level version of EuroQol-5-dimension (EQ-5D-3L) and visual analogue scale (EQ-VAS) questionnaires.
Of 659 eligible patients surveyed, 202 patients (30.65%) had experienced symptoms of hypoglycemia.
HRQoL was significantly lower among patients reporting at least one of hypoglycemic symptoms, measured by EQ-VAS scores (mean±SD; 73.66±13.18, 73.56±15.10, or 68.93±14.76 vs.
77.01±13.02, one-way ANOVA; p=0.006) and EQ-5D-3L index scores (0.62±0.47, 0.68±0.38, or 0.58±0.51 vs.
0.79±0.31, one-way ANOVA; p<0.001) for mild, moderate, or severe/very severe hypoglycemic patients compared with patients without hypoglycemic symptoms.
After adjusting for confounding factors in a multiple linear regression model, patients with hypoglycemic symptoms either mild, moderate, or severe/very severe demonstrated significantly higher impairment for EQ-VAS and EQ-5D indexes than those who did not experience hypoglycemic symptoms.
In conclusion, our study showed decreased HRQoL determined by EQ-5D and EQ-VAS in patients reporting symptoms of hypoglycemia compared with patients not reporting hypoglycemic symptoms, relative to severity of hypoglycemia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pratipanawatr, Thongchai& Satirapoj, Bancha& Ongphiphadhanakul, Boonsong& Suwanwalaikorn, Sompongse& Nitiyanant, Wannee. 2019. Impact of Hypoglycemia on Health-Related Quality of Life among Type 2 Diabetes: A Cross-Sectional Study in Thailand. Journal of Diabetes Research،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1173075
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pratipanawatr, Thongchai…[et al.]. Impact of Hypoglycemia on Health-Related Quality of Life among Type 2 Diabetes: A Cross-Sectional Study in Thailand. Journal of Diabetes Research No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1173075
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pratipanawatr, Thongchai& Satirapoj, Bancha& Ongphiphadhanakul, Boonsong& Suwanwalaikorn, Sompongse& Nitiyanant, Wannee. Impact of Hypoglycemia on Health-Related Quality of Life among Type 2 Diabetes: A Cross-Sectional Study in Thailand. Journal of Diabetes Research. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1173075
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173075
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر