Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana
المؤلفون المشاركون
Plange-Rhule, Jacob
Eastwood, John B.
Micah, Frank B.
Banerjee, Debasish
Chitalia, Nihil
Kumi, Kwabena
Cappuccio, Francesco P.
المصدر
International Journal of Hypertension
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Hypertension, particularly pulse pressure [PP] is a major risk factor for end-stage renal disease.
However, the effect of individual components of hypertension namely PP, systolic [SBP] and diastolic blood pressure [DBP] on kidney function, in the general African population is unknown.
Methods.
Data were collected on 944 participants [aged 40-75 y], living in villages in the area around the city of Kumasi, Ghana, on demographics, medications, height, weight, BP and 24-hour creatinine clearance (CrCl).
Results.
The demographic and clinical characteristics were: age 55(11) [mean (SD)] years, females 62%, rural village-dwellers 52%, diabetes 1·5%, BMI 21(4) kg/m2, 24-hourCrCl as a measure of glomerular filtration rate (GFR) 84(23) ml/min/1.73 m2.
29% had BP >140/90 mmHg; SBP and DBP were 125/74(26/14) mmHg, PP was 51(17) mmHg.
PP increased with age by 0.55(95% CI: 0.46,0.64) mmHg/year.
PP was higher (53(17) v 49(15) mmHg; p < 0.001) in the semiurban participants.
GFR decreased both with increasing PP [-0.19 (-0.27,-0.10 ml/min/1.73 m2/mmHg; p < 0.001] and SBP [-0.09 (-0.14,-0.03) ml/min/1.73 m2/mmHg; p < 0.001] but there was no significant relationship with DBP [-0.04 (-0.15,0.06)].
After adjusting for SBP, the relationship between GFR and PP became steeper [-0.31 (-0.50,-0.12) ml/min/1.73 m2/mmHg; p < 0.001].
Using multivariate regression analysis that included PP, age, gender, BMI, only increasing age [-0.75 (-0.88,-0.62)] and decreasing BMI [0.49 (0.16,0.81)] were associated with decreased kidney function.
Conclusions.
In this homogeneous West-African population, PP increased with age and had a steeper relationship with declining kidney function than SBP or DBP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Banerjee, Debasish& Plange-Rhule, Jacob& Chitalia, Nihil& Kumi, Kwabena& Micah, Frank B.& Cappuccio, Francesco P.…[et al.]. 2018. Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana. International Journal of Hypertension،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1173191
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Banerjee, Debasish…[et al.]. Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana. International Journal of Hypertension No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1173191
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Banerjee, Debasish& Plange-Rhule, Jacob& Chitalia, Nihil& Kumi, Kwabena& Micah, Frank B.& Cappuccio, Francesco P.…[et al.]. Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana. International Journal of Hypertension. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1173191
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173191
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر