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Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana
المؤلفون المشاركون
Plange-Rhule, Jacob
Eastwood, John B.
Micah, Frank B.
Banerjee, Debasish
Chitalia, Nihil
Kumi, Kwabena
Cappuccio, Francesco P.
المصدر
International Journal of Hypertension
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Hypertension, particularly pulse pressure [PP] is a major risk factor for end-stage renal disease.
However, the effect of individual components of hypertension namely PP, systolic [SBP] and diastolic blood pressure [DBP] on kidney function, in the general African population is unknown.
Methods.
Data were collected on 944 participants [aged 40-75 y], living in villages in the area around the city of Kumasi, Ghana, on demographics, medications, height, weight, BP and 24-hour creatinine clearance (CrCl).
Results.
The demographic and clinical characteristics were: age 55(11) [mean (SD)] years, females 62%, rural village-dwellers 52%, diabetes 1·5%, BMI 21(4) kg/m2, 24-hourCrCl as a measure of glomerular filtration rate (GFR) 84(23) ml/min/1.73 m2.
29% had BP >140/90 mmHg; SBP and DBP were 125/74(26/14) mmHg, PP was 51(17) mmHg.
PP increased with age by 0.55(95% CI: 0.46,0.64) mmHg/year.
PP was higher (53(17) v 49(15) mmHg; p < 0.001) in the semiurban participants.
GFR decreased both with increasing PP [-0.19 (-0.27,-0.10 ml/min/1.73 m2/mmHg; p < 0.001] and SBP [-0.09 (-0.14,-0.03) ml/min/1.73 m2/mmHg; p < 0.001] but there was no significant relationship with DBP [-0.04 (-0.15,0.06)].
After adjusting for SBP, the relationship between GFR and PP became steeper [-0.31 (-0.50,-0.12) ml/min/1.73 m2/mmHg; p < 0.001].
Using multivariate regression analysis that included PP, age, gender, BMI, only increasing age [-0.75 (-0.88,-0.62)] and decreasing BMI [0.49 (0.16,0.81)] were associated with decreased kidney function.
Conclusions.
In this homogeneous West-African population, PP increased with age and had a steeper relationship with declining kidney function than SBP or DBP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Banerjee, Debasish& Plange-Rhule, Jacob& Chitalia, Nihil& Kumi, Kwabena& Micah, Frank B.& Cappuccio, Francesco P.…[et al.]. 2018. Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana. International Journal of Hypertension،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1173191
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Banerjee, Debasish…[et al.]. Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana. International Journal of Hypertension No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1173191
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Banerjee, Debasish& Plange-Rhule, Jacob& Chitalia, Nihil& Kumi, Kwabena& Micah, Frank B.& Cappuccio, Francesco P.…[et al.]. Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana. International Journal of Hypertension. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1173191
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1173191
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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