Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania
المؤلفون المشاركون
Kapeleka, Jones A.
Sauli, Elingarami
Sadik, Omowunmi
Ndakidemi, Patrick A.
المصدر
Journal of Environmental and Public Health
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-11
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Biomonitoring of pesticides exposure has currently become a matter of great public concern due to the potential health effects of pesticides.
This study assessed levels of acetylcholinesterase (AChE) inhibition and associated health effects in uncontrolled smallholder farming systems in rural Tanzania.
A cross-sectional study was conducted of 90 exposed farmers and 61 nonexposed controls from horticultural zones.
A structured questionnaire was administered, and a capillary blood sample of 10 μl was used to measure AChE activity using an Erythrocyte Acetylcholinesterase Test Mate Photometric Analyzer kit (Model 400).
A multiple logistic regression model was used to investigate determinants of pesticide exposure.
The study revealed that smallholder farmers are occupationally exposed to pesticides.
Exposed farmers had significantly lower AChE levels.
The use of personal protective equipment (PPE) did not significantly reduce the likelihood of AChE inhibition.
Women, younger and older farmers, and underweight, overweight, and obese farmers were at increased risk of AChE inhibition.
Increase in age (10 years) increased likelihood of AChE inhibition by 6.7%, while decrease in BMI increased likelihood of AChE inhibition by 86.7% while increased pesticides contact hours increased risk of having lower AChE at about 3 times.
The number of exposure symptoms (14.10 ± 7.70) was higher in exposed farmers than unexposed.
Self-reported symptoms are confirmed to correlate to lower AChE.
Prevalence of tiredness (71.6% against 15.5%), fatigue (64.8% against 27.6%), soreness in joints (59.1% against 20.7%), thirst (52.3% against 12.1%), skin irritation (52.1% against 17.2%), salivation and abdominal pain (50% against 8.6% and 31.0%, respectively), muscle weakness (47.7% against 24.1%), and memory loss (47.7% against and 29.3%) differed significantly between exposed and control.
This study provides useful information regarding the level of occupational and environmental exposure to pesticides in smallholder horticultural production systems.
Pesticides use needs to be controlled at farm level by developing pesticides monitoring and surveillance systems.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kapeleka, Jones A.& Sauli, Elingarami& Sadik, Omowunmi& Ndakidemi, Patrick A.. 2019. Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania. Journal of Environmental and Public Health،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1174032
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kapeleka, Jones A.…[et al.]. Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania. Journal of Environmental and Public Health No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1174032
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kapeleka, Jones A.& Sauli, Elingarami& Sadik, Omowunmi& Ndakidemi, Patrick A.. Biomonitoring of Acetylcholinesterase (AChE) Activity among Smallholder Horticultural Farmers Occupationally Exposed to Mixtures of Pesticides in Tanzania. Journal of Environmental and Public Health. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1174032
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1174032
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر