Predictive Factors of Positive Circumferential and Longitudinal Margins in Early T3 Colorectal Cancer Resection
المؤلفون المشاركون
Balbaa, M. Ashraf
Elkady, Noha
Abdelrahman, Emad M.
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-27
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Malignant involvement of circumferential resection margin (CRM) and longitudinal resection margin (LRM) after surgical resection of colorectal cancer (CRC) are associated with higher rates of recurrence and development of distant metastasis.
This can influence the overall patient’s prognosis.
The aim of the current study was to identify pathological factors as predictors for the involvement of resection margins in early T3 CRC.
Patients and Methods.
Fifty patients radiologically diagnosed to have cT3a/b (CRC) were included in the study.
After resection, the pathological examination was performed to identify patients with positive CRM and/or LRM.
Relations between the different pathological parameters and the CMR and LRM involvements were assessed.
Results.
Positive CRM was present in 17 cases (34%), while positive LRM was found in 6 cases (12%).
The involvement of both margins was significantly associated with rectal tumors and tumors with infiltrative gross appearance, grade III, deeper invasion, and positive lymph node metastases.
Also, there was a significant association between both margins’ positivity and other pathological parameters as signet ring carcinoma, tumor budding, perineural and vascular invasion, high microvessel density (MVD), and sinusoidal vascular pattern, while the presence of necrosis and infiltrative advancing tumor front was significantly associated with CRM involvement only.
The depth of tumor invasion and signet ring carcinoma were identified as independent predictor factors for positive CRM and LRM, respectively.
Conclusion.
Preoperative identification of these pathological parameters can be a guide to tailor the management plan accordingly.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Balbaa, M. Ashraf& Elkady, Noha& Abdelrahman, Emad M.. 2020. Predictive Factors of Positive Circumferential and Longitudinal Margins in Early T3 Colorectal Cancer Resection. International Journal of Surgical Oncology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1174162
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Balbaa, M. Ashraf…[et al.]. Predictive Factors of Positive Circumferential and Longitudinal Margins in Early T3 Colorectal Cancer Resection. International Journal of Surgical Oncology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1174162
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Balbaa, M. Ashraf& Elkady, Noha& Abdelrahman, Emad M.. Predictive Factors of Positive Circumferential and Longitudinal Margins in Early T3 Colorectal Cancer Resection. International Journal of Surgical Oncology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1174162
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1174162
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر