Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow
المؤلفون المشاركون
Mohammadpour, Amir Hooshang
Sahebkar, Amirhossein
Naserifar, Mahshid
Ataei, Mahshid
Behzadian, Nadia
Dastani, Mostafa
Hosseinjani, Hesamoddin
المصدر
International Journal of Vascular Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Coronary slow flow (CSF) is an important angiographic entity that is characterized by delayed opacification of coronary arteries in the absence of epicardial occlusive disease.
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase.
Elevated levels of ADMA cause the induction of endothelial dysfunction and thus promote atherosclerosis.
This study was aimed at determining the role of ADMA in the development of CSF.
One hundred twenty-nine subjects who fulfilled the inclusion criteria were enrolled in this study.
According to coronary angiography results, these subjects were divided into five groups.
The serum concentration of ADMA was measured in these subjects.
In this study, there was no significant correlation between serum concentrations of ADMA and mean corrected TIMI frame count (CTFC) (P>0.05).
However, the ADMA level was significantly correlated with CTFC in the left anterior descending (LAD) coronary artery in patients with CSF (r=−0.381, P=0.045).
Also, plasma ADMA levels were significantly higher in patients with CSF and without CAD compared to patients without CSF and with CAD (50-90%) (P=0.034).
Besides, serum concentrations of ADMA were significantly higher in subjects with BMI<25 kg/m2 compared with those having BMI>30 kg/m2 (P=0.003).
It was also shown that the levels of ADMA were significantly higher in subjects with age as a cardiovascular risk factor compared with those without this risk factor (P=0.024).
Further studies with larger population sizes are needed to confirm the present findings on the association between the serum concentrations of ADMA and CSF.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Naserifar, Mahshid& Ataei, Mahshid& Behzadian, Nadia& Mohammadpour, Amir Hooshang& Dastani, Mostafa& Sahebkar, Amirhossein…[et al.]. 2020. Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow. International Journal of Vascular Medicine،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1174218
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Naserifar, Mahshid…[et al.]. Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow. International Journal of Vascular Medicine No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1174218
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Naserifar, Mahshid& Ataei, Mahshid& Behzadian, Nadia& Mohammadpour, Amir Hooshang& Dastani, Mostafa& Sahebkar, Amirhossein…[et al.]. Evaluation of the Correlation between Serum Concentrations of Asymmetric Dimethylarginine and Corrected TIMI Frame Count in Patients with Slow Coronary Flow. International Journal of Vascular Medicine. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1174218
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1174218
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر