Serum Endothelin-1 Correlates with Myocardial Injury and Independently Predicts Adverse Cardiac Events in Non-ST-Elevation Acute Myocardial Infarction
المؤلفون المشاركون
Setianto, Budi Yuli
Sukmasari, Indah
Puspitawati, Ira
Hartopo, Anggoro Budi
المصدر
International Journal of Vascular Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Serum endothelin-1 is increasingly released in acute myocardial infarction, by necrotic cardiomyocytes.
In non-ST-elevation acute myocardial infarction (Non-STEMI), increased serum endothelin-1 on-admission may have clinical significance during acute hospitalisation events.
Objective.
The purpose of this study is to investigate whether increased serum endothelin-1 level predict adverse cardiac events in patients hospitalized with Non-STEMI.
Methods.
The design of this research was a prospective cohort study.
Consecutive subjects with Non-STEMI undergoing symptom onset ≤24 hour were enrolled and observed during intensive hospitalization.
Serum endothelin-1, troponin-I, and hs-C reactive protein were measured from peripheral blood taken on-admission.
In-hospital adverse cardiac events were a composite of death, acute heart failure, cardiogenic shock, reinfarction, and resuscitated VT/VF.
Results.
We enrolled 66 subjects.
The incidence of in-hospital adverse cardiac events is 13.6% (10 out of 66 subjects).
Serum endothelin-1 level was significantly higher in subjects with in-hospital adverse cardiac events.
Subjects with endothelin-1 level >2.59 pg/mL independently predicted adverse cardiac events in hospitalised Non-STEMI patients (adjusted odds ratio 44.43, 95% confidence interval: 1.44-1372.99, p value 0.03).
The serum endothelin-1 level was correlated with serum troponin I level (correlation coefficient of 0.413, p value 0.012).
Conclusion.
Increased serum endothelin-1 on-admission correlated with increased troponin-I and independently predicted in-hospital adverse cardiac events in patients with Non-STEMI.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hartopo, Anggoro Budi& Sukmasari, Indah& Puspitawati, Ira& Setianto, Budi Yuli. 2020. Serum Endothelin-1 Correlates with Myocardial Injury and Independently Predicts Adverse Cardiac Events in Non-ST-Elevation Acute Myocardial Infarction. International Journal of Vascular Medicine،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1174239
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hartopo, Anggoro Budi…[et al.]. Serum Endothelin-1 Correlates with Myocardial Injury and Independently Predicts Adverse Cardiac Events in Non-ST-Elevation Acute Myocardial Infarction. International Journal of Vascular Medicine No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1174239
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hartopo, Anggoro Budi& Sukmasari, Indah& Puspitawati, Ira& Setianto, Budi Yuli. Serum Endothelin-1 Correlates with Myocardial Injury and Independently Predicts Adverse Cardiac Events in Non-ST-Elevation Acute Myocardial Infarction. International Journal of Vascular Medicine. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1174239
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1174239
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر