Increased Serum Uric Acid Level Is a Risk Factor for Left Ventricular Hypertrophy but Not Independent of eGFR in Patients with Type 2 Diabetic Kidney Disease
المؤلفون المشاركون
Fan, Ying
Jian, Guihua
Wang, Niansong
Zeng, Chuchu
Cheng, Dongsheng
Sheng, Xiaohua
Chen, Yuqiang
Li, Junhui
Bao, Hongda
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Although the relation between serum uric acid (SUA) and left ventricular hypertrophy (LVH) has been studied for decades, however, their association remains debatable.
Methods.
This is a retrospective study in which a total of 435 hospitalized Chinese patients with type 2 DKD were enrolled.
The subjects were stratified into quartiles according to SUA level.
LVH was assessed by two-dimensional guided M-mode echocardiography.
Results.
There was a significant increase in the prevalence of LVH in patients with type 2 DKD across SUA quartiles (28.9, 26.5, 36.1, and 49.5%; p<0.001).
The Spearman analysis indicated that SUA was positively correlated to LVMI and negatively correlated to eGFR.
The logistic regression analysis revealed that the odd ratio for LVH in the highest SUA quartile was 2.439 (95% CI 1.265–4.699; p=0.008; model 1) or 2.576 (95% CI 1.150–5.768; p=0.021; model 2) compared with that in the lowest SUA quartile.
However, there was no significant increased risk of LVH in the subjects with the highest SUA quartile after adjusting the eGFR (OR = 1.750; 95% CI 0.685–4.470; p=0.242; model 3).
Conclusions.
In selected population, such as type 2 DKD, the elevated SUA level is positively linked with the increased risk of LVH, but this relationship is not independent of eGFR.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zeng, Chuchu& Cheng, Dongsheng& Sheng, Xiaohua& Jian, Guihua& Fan, Ying& Chen, Yuqiang…[et al.]. 2017. Increased Serum Uric Acid Level Is a Risk Factor for Left Ventricular Hypertrophy but Not Independent of eGFR in Patients with Type 2 Diabetic Kidney Disease. Journal of Diabetes Research،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174380
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zeng, Chuchu…[et al.]. Increased Serum Uric Acid Level Is a Risk Factor for Left Ventricular Hypertrophy but Not Independent of eGFR in Patients with Type 2 Diabetic Kidney Disease. Journal of Diabetes Research No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1174380
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zeng, Chuchu& Cheng, Dongsheng& Sheng, Xiaohua& Jian, Guihua& Fan, Ying& Chen, Yuqiang…[et al.]. Increased Serum Uric Acid Level Is a Risk Factor for Left Ventricular Hypertrophy but Not Independent of eGFR in Patients with Type 2 Diabetic Kidney Disease. Journal of Diabetes Research. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1174380
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1174380
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر