Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples
المؤلفون المشاركون
da Silva, Danielle Cristina
Oliveira, Cláudio Celestino
المصدر
Journal of Analytical Methods in Chemistry
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-01
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Method for extraction and determination of amoxicillin, caffeine, ciprofloxacin, norfloxacin, tetracycline, diclofenac, ibuprofen, nimesulide, levonorgestrel, and 17α-ethynylestradiol exploiting micellar liquid chromatography with PDA detector and solid-phase extraction was proposed.
The usage of toxic solvents was low; the chromatographic separation of the medicaments was performed using a C18 column and mobile phases A and B containing 15.0% (v/v) ethanol, 3.0% (m/v) sodium dodecyl sulfate (SDS), and 0.02 mol·L−1 phosphate at pHs 7.0 and 8.0, respectively.
The method is simple, selective, and fast, and the analytes were separated in 23.0 min.
For extraction, 1000 mL of sample containing 2.0% (v/v) ethanol and 0.002 mol·L−1 citric acid at pH 2.50 was loaded through a 1000 mg of C18 cartridge.
The analytes were eluted using 3.0 mL of ethanol, which were evaporated and redissolved in 0.5 mL of mobile phase.
Concentration factors better than 1200, except amoxicillin (224), were obtained.
The analytical curves were linear (R2 better than 0.992); LOD and LOQ n=10 presented values in the range of 0.019–0.247 and 0.058–0.752 mg·L−1, respectively.
Recoveries of 99% were obtained, and the results are in agreement with those obtained by the comparative methods.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
da Silva, Danielle Cristina& Oliveira, Cláudio Celestino. 2018. Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples. Journal of Analytical Methods in Chemistry،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1176655
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
da Silva, Danielle Cristina& Oliveira, Cláudio Celestino. Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples. Journal of Analytical Methods in Chemistry No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1176655
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
da Silva, Danielle Cristina& Oliveira, Cláudio Celestino. Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples. Journal of Analytical Methods in Chemistry. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1176655
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1176655
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر