Evaluation of Potential Drug-Drug Interactions with Medications Prescribed to Geriatric Patients in a Tertiary Care Hospital
المؤلفون المشاركون
Kamath, Ashwin
Shenoy, Ashok K.
Chowta, Mukta N.
Kamath, Priyanka
Shetty, Varsha
Chowta K, Nithyananda
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-09
دولة النشر
مصر
عدد الصفحات
6
الملخص EN
Background and Objectives.
The drugs most commonly implicated in major potential interactions are those used in the day-to-day clinical management of elderly patients with chronic diseases.
This study is planned to evaluate the profile of drug-drug interactions in the medications prescribed to elderly population and also to identify the possible predictors for potential drug-drug interactions in the elderly.
Methods.
This cross-sectional study included patients aged above 60 years with a minimum of two drugs in the prescriptions.
Data were collected from medical prescriptions and patients' medical records.
The data collected included demographic characteristics such as age, gender, height, weight, educational status, socioeconomic status, medical history, and medications prescribed.
The prescriptions were analyzed for the potential drug interactions using Lexi-Interact™ Online, an online software to check drug-drug interactions.
Results.
A total of 209 patients were included in the study, among them 104 (49.8%) were males and 105 (50.2%) were females.
The mean number of medications received was 6.53 ± 2.15 per prescription.
Around 138 (66%) patients received more than six medications.
The mean number of potential drug interactions seen in the prescription of these patients was 3.17 ± 2.78.
Around 18.2% patients had more than five drug interactions.
Major drug interactions were observed in 21.42% of cases.
Around 3.02% of drug interactions belonged to risk category X, i.e., to be avoided.
Logistic regression analysis showed that age above 70 years was associated with the presence of drug interactions.
Increased number of medication was independently associated with the occurrence of drug interactions.
The presence of drug interactions was not associated with increased number of comorbidities.
Conclusion.
A significant number of potential drug-drug interactions were seen in the prescriptions of elderly patients.
Increasing age and polypharmacy were identified as the predictors of potential drug interactions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shetty, Varsha& Chowta, Mukta N.& Chowta K, Nithyananda& Shenoy, Ashok K.& Kamath, Ashwin& Kamath, Priyanka. 2018. Evaluation of Potential Drug-Drug Interactions with Medications Prescribed to Geriatric Patients in a Tertiary Care Hospital. Journal of Aging Research،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1180752
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shetty, Varsha…[et al.]. Evaluation of Potential Drug-Drug Interactions with Medications Prescribed to Geriatric Patients in a Tertiary Care Hospital. Journal of Aging Research No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1180752
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shetty, Varsha& Chowta, Mukta N.& Chowta K, Nithyananda& Shenoy, Ashok K.& Kamath, Ashwin& Kamath, Priyanka. Evaluation of Potential Drug-Drug Interactions with Medications Prescribed to Geriatric Patients in a Tertiary Care Hospital. Journal of Aging Research. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1180752
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1180752
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر