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Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer’s Disease
المؤلفون المشاركون
Ricevuti, Giovannoi
Torrisi, Filippo
Venturini, Letizia
Granato, Maria
Lupo, Giuseppe Francesco Damiano
Capelli, Enrica
Fassina, Lorenzo
المصدر
Journal of Healthcare Engineering
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The aim of the present study was to investigate on the effects of a low-frequency pulsed electromagnetic field (LF-PEMF) in an experimental cell model of Alzheimer’s disease (AD) to assess new therapies that counteract neurodegeneration.
In recent scientific literature, it is documented that the deep brain stimulation via electromagnetic fields (EMFs) modulates the neurophysiological activity of the pathological circuits and produces clinical benefits in AD patients.
EMFs are applied for tissue regeneration because of their ability to stimulate cell proliferation and immune functions via the HSP70 protein family.
However, the effects of EMFs are still controversial and further investigations are required.
Our results demonstrate the ability of our LF-PEMF to modulate gene expression in cell functions that are dysregulated in AD (i.e., BACE1) and that these effects can be modulated with different treatment conditions.
Of relevance, we will focus on miRNAs regulating the pathways involved in brain degenerative disorders.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Capelli, Enrica& Torrisi, Filippo& Venturini, Letizia& Granato, Maria& Fassina, Lorenzo& Lupo, Giuseppe Francesco Damiano…[et al.]. 2017. Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer’s Disease. Journal of Healthcare Engineering،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1180864
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Capelli, Enrica…[et al.]. Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer’s Disease. Journal of Healthcare Engineering No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1180864
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Capelli, Enrica& Torrisi, Filippo& Venturini, Letizia& Granato, Maria& Fassina, Lorenzo& Lupo, Giuseppe Francesco Damiano…[et al.]. Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer’s Disease. Journal of Healthcare Engineering. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1180864
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1180864
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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