Inhibitory Effect of Propolis on Platelet Aggregation In Vitro
المؤلفون المشاركون
Zhang, Yunxiang
Yang, Ting-Ting
Xia, Liu
Zhang, Wei-Fen
Wang, Jia-Fu
Wu, Ya-Ping
المصدر
Journal of Healthcare Engineering
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Platelet hyperactivity plays an important role in arterial thrombosis and atherosclerosis.
The present study was aimed to investigate the effects of different extracts of propolis and components of flavonoids on platelet aggregation.
Platelet-rich plasma was prepared and incubated in vitro with different concentrations of the tested extracts and components of flavonoids.
Platelets aggregation was induced by different agonists including adenosine diphosphate (ADP, 10 μM), thrombin receptor activator peptide (TRAP, 50 μM), and collagen (5 μg/mL).
At 25 mg/L to 300 mg/mL, the water extract propolis (WEP) inhibited three agonists-induced platelet aggregations in a dose-dependent manner.
The flavonoids isolated from the propolis also showed markedly inhibited platelet aggregation induced by collagen, ADP, and TRAP, respectively.
The components including caffeic acid phenethyl ester (CAPE), galangin, apigenin, quercetin, kaempferol, ferulic acid, rutin, chrysin, pinostrobin, and pinocembrin and their abilities of inhibiting platelet aggregation were studied.
It was concluded that propolis had an antiplatelet action in which flavonoids were mainly implicated.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Yunxiang& Yang, Ting-Ting& Xia, Liu& Zhang, Wei-Fen& Wang, Jia-Fu& Wu, Ya-Ping. 2017. Inhibitory Effect of Propolis on Platelet Aggregation In Vitro. Journal of Healthcare Engineering،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1180880
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Yunxiang…[et al.]. Inhibitory Effect of Propolis on Platelet Aggregation In Vitro. Journal of Healthcare Engineering No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1180880
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Yunxiang& Yang, Ting-Ting& Xia, Liu& Zhang, Wei-Fen& Wang, Jia-Fu& Wu, Ya-Ping. Inhibitory Effect of Propolis on Platelet Aggregation In Vitro. Journal of Healthcare Engineering. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1180880
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1180880
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر