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Strategies to Lower In-Hospital Mortality in STEMI Patients with Primary PCI: Analysing Two Years Data from a High-Volume Interventional Centre
المؤلفون المشاركون
Burlacu, Alexandru
Artene, Bogdan
Simion, Paul
Nedelciuc, Igor
Covic, Adrian
Tinica, Grigore
المصدر
Journal of Interventional Cardiology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-01
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
We aimed to analyse data from our high-volume interventional centre (>1000 primary percutaneous coronary interventions (PCI) per year) searching for predictors of in-hospital mortality in acute myocardial infarction (MI) patients.
Moreover, we looked for realistic strategies and interventions for lowering in-hospital mortality under the “5 percent threshold.” Background.
Although interventional and medical treatment options are constantly expanding, recent studies reported a residual in-hospital mortality ranging between 5 and 10 percent after primary PCI.
Current data sustain that mortality after ST-elevation MI will soon reach a point when cannot be reduced any further.
Methods.
In this retrospective observational single-centre cohort study, we investigated two-year data from a primary PCI registry including 2035 consecutive patients.
Uni- and multivariate analysis were performed to identify independent predictors for in-hospital mortality.
Results.
All variables correlated with mortality in univariate analysis were introduced in a stepwise multivariate linear regression model.
Female gender, hypertension, depressed left ventricular ejection fraction, history of MI, multivessel disease, culprit left main stenosis, and cardiogenic shock proved to be independent predictors of in-hospital mortality.
The model was validated for sensitivity and specificity using receiver operating characteristic curve.
For our model, variables can predict in-hospital mortality with a specificity of 96.60% and a sensitivity of 84.68% (p<0.0001, AUC = 0.93, 95% CI 0.922–0.944).
Conclusions.
Our analysis identified a predictive model for in-hospital mortality.
The majority of deaths were due to cardiogenic shock.
We suggested that in order to lower mortality under 5 percent, focus should be on creating a cardiogenic shock system based on the US experience.
A shock hub-centre, together with specific transfer algorithms, mobile interventional teams, ventricular assist devices, and surgical hybrid procedures seem to be the next step toward a better management of ST-elevation MI patients and subsequently lower death rates.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Burlacu, Alexandru& Tinica, Grigore& Nedelciuc, Igor& Simion, Paul& Artene, Bogdan& Covic, Adrian. 2019. Strategies to Lower In-Hospital Mortality in STEMI Patients with Primary PCI: Analysing Two Years Data from a High-Volume Interventional Centre. Journal of Interventional Cardiology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1181215
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Burlacu, Alexandru…[et al.]. Strategies to Lower In-Hospital Mortality in STEMI Patients with Primary PCI: Analysing Two Years Data from a High-Volume Interventional Centre. Journal of Interventional Cardiology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1181215
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Burlacu, Alexandru& Tinica, Grigore& Nedelciuc, Igor& Simion, Paul& Artene, Bogdan& Covic, Adrian. Strategies to Lower In-Hospital Mortality in STEMI Patients with Primary PCI: Analysing Two Years Data from a High-Volume Interventional Centre. Journal of Interventional Cardiology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1181215
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1181215
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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