Bacteriophages and Their Immunological Applications against Infectious Threats
المؤلفون المشاركون
Spadini, Sara
Lamanna, Jacopo
Ferro, Mattia
Criscuolo, Elena
Burioni, Roberto
المصدر
Journal of Immunology Research
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-18
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Bacteriophage therapy dates back almost a century, but the discovery of antibiotics led to a rapid decline in the interests and investments within this field of research.
Recently, the novel threat of multidrug-resistant bacteria highlighted the alarming drop in research and development of new antibiotics: 16 molecules were discovered during 1983–87, 10 new therapeutics during the nineties, and only 5 between 2003 and 2007.
Phages are therefore being reconsidered as alternative therapeutics.
Phage display technique has proved to be extremely promising for the identification of effective antibodies directed against pathogens, as well as for vaccine development.
At the same time, conventional phage therapy uses lytic bacteriophages for treatment of infections and recent clinical trials have shown great potential.
Moreover, several other approaches have been developed in vitro and in vivo using phage-derived proteins as antibacterial agents.
Finally, their use has also been widely considered for public health surveillance, as biosensor phages can be used to detect food and water contaminations and prevent bacterial epidemics.
These novel approaches strongly promote the idea that phages and their proteins can be exploited as an effective weapon in the near future, especially in a world which is on the brink of a “postantibiotic era.”
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Criscuolo, Elena& Spadini, Sara& Lamanna, Jacopo& Ferro, Mattia& Burioni, Roberto. 2017. Bacteriophages and Their Immunological Applications against Infectious Threats. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1181751
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Criscuolo, Elena…[et al.]. Bacteriophages and Their Immunological Applications against Infectious Threats. Journal of Immunology Research No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1181751
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Criscuolo, Elena& Spadini, Sara& Lamanna, Jacopo& Ferro, Mattia& Burioni, Roberto. Bacteriophages and Their Immunological Applications against Infectious Threats. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1181751
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1181751
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر