Mannose-Binding Lectin: Biologic Characteristics and Role in the Susceptibility to Infections and Ischemia-Reperfusion Related Injury in Critically Ill Neonates
المؤلفون المشاركون
Bersani, Iliana
Auriti, Cinzia
Prencipe, Giusi
Mondì, Vito
Moriondo, Maria
Bertaina, Chiara
Inglese, Rita
المصدر
Journal of Immunology Research
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-26
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
The mannose-binding lectin (MBL) is a member of the collectin family, belonging to the innate immunity system.
Genetic, biologic, and clinical properties of MBL have been widely investigated throughout the last decades, although some interesting aspects of its potential clinical relevance are still poorly understood.
Low circulating concentrations of MBL have been associated with increased risk of infection and poor neurologic outcome in neonates.
On the other hand, an excessive and uncontrolled inflammatory response by the neonatal intestine after the exposure to luminal bacteria, leading to an increased production of MBL, may be involved in the onset of necrotizing enterocolitis.
The purpose of the present review is to summarize the current knowledge about genetic and biologic characteristics of MBL and its role in the susceptibility to infections and to ischemia-reperfusion related tissue injuries to better explore its clinical relevance during the perinatal period and the possible future therapeutic applications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Auriti, Cinzia& Prencipe, Giusi& Moriondo, Maria& Bersani, Iliana& Bertaina, Chiara& Mondì, Vito…[et al.]. 2017. Mannose-Binding Lectin: Biologic Characteristics and Role in the Susceptibility to Infections and Ischemia-Reperfusion Related Injury in Critically Ill Neonates. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1182048
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Auriti, Cinzia…[et al.]. Mannose-Binding Lectin: Biologic Characteristics and Role in the Susceptibility to Infections and Ischemia-Reperfusion Related Injury in Critically Ill Neonates. Journal of Immunology Research No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1182048
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Auriti, Cinzia& Prencipe, Giusi& Moriondo, Maria& Bersani, Iliana& Bertaina, Chiara& Mondì, Vito…[et al.]. Mannose-Binding Lectin: Biologic Characteristics and Role in the Susceptibility to Infections and Ischemia-Reperfusion Related Injury in Critically Ill Neonates. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1182048
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182048
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر