Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study
المؤلفون المشاركون
de Vries, Johanna I. P.
Voskuyl, Alexandre E.
Kroese, S. J.
Lely, A. T.
van Laar, J. M.
Derksen, R. H. W. M.
Fritsch-Stork, R. D. E.
Abheiden, Carolien N. H.
Blomjous, Birgit S.
Bultink, Irene E. M.
de Boer, Marjon A.
المصدر
Journal of Immunology Research
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
To investigate disease activity around and during pregnancy and pregnancy outcome in women with systemic lupus erythematosus (SLE) considering antiphospholipid antibody status.
Moreover, differences between first and consecutive pregnancies were examined.
Methods.
Pregnancies > 16 weeks gestation of SLE patients receiving joint care from rheumatologists and gynecologists in two tertiary centers in the Netherlands between 2000 and 2015 were included.
Disease activity, flare rate, and pregnancy outcomes and complications were assessed.
Results.
Ninety-six women (84% Caucasian) with 144 pregnancies were included.
The median SLE(P)DAI score was 2 before, during, and after pregnancy.
Flare rates were 6.3%, 20.1%, and 15.3%, respectively.
Severe hypertensive disorder of pregnancy, intrauterine fetal death, preterm birth, and small-for-gestational age infants occurred in 18.1%, 4.1%, 32.7%, and 14.8%, respectively.
Complication rates were similar in the first and consecutive pregnancies.
Half of the women did not experience any pregnancy complication whereas 42.7% developed a complication during all pregnancies.
Mean number of pregnancies was 2.4 and live births 1.7.
Conclusion.
In this SLE population with low disease activity, pregnancy complications were present irrespective of antiphospholipid antibody status.
Furthermore, there were no differences in complication rates between the first and consecutive pregnancies as seen in healthy mothers.
This information is useful for patient counseling.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kroese, S. J.& Abheiden, Carolien N. H.& Blomjous, Birgit S.& van Laar, J. M.& Derksen, R. H. W. M.& Bultink, Irene E. M.…[et al.]. 2017. Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1182126
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kroese, S. J.…[et al.]. Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study. Journal of Immunology Research No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1182126
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kroese, S. J.& Abheiden, Carolien N. H.& Blomjous, Birgit S.& van Laar, J. M.& Derksen, R. H. W. M.& Bultink, Irene E. M.…[et al.]. Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1182126
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182126
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر