Serum Cytokine Levels and Their Relation to Clinical Features in Patients with Autoimmune Liver Diseases
المؤلفون المشاركون
Kiassov, Andrey P.
Akberova, Dilyara
Abdulganieva, Diana
المصدر
Journal of Immunology Research
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Serum cytokine levels were explored in a combined group of patients with autoimmune liver diseases (AILDs) and separately in patients with autoimmune hepatitis (AIH) and overlap syndrome.
Overall, 60 patients with AILD, among them 32 patients with AIH and 28 patients with overlap syndrome, were included in the cross-sectional study.
Serum cytokine levels were measured at baseline and compared to those of 21 healthy controls.
Patients with AILD had significantly higher levels of IL-6 (0.70 (range 0.17–99.86) in patients with AILD compared to 0.40 (range 0.14–2.65) in controls, p<0.01), IL-8 (1.66 (0.45–34.58) versus 0.53 (0.35–2.38), resp., p<0.01), and TNF-α (2.61 (0.23–120.88) versus 1.65 (0.21–7.54), resp., p<0.01).
Adjusted logistic regression analysis revealed a pronounced relation of IL-8 and AILD, 48.36 (3.63–643.60), as well as AIH, 18.54 (1.08–318.54), and overlap syndrome, 23.85 (2.37–240.23), while the associations between the level of other cytokines and AILD were assessed as nonsignificant.
In the language of absolute numbers, the increase of IL-8 serum level by 1 pg/mL had increased the chance for a patient to find himself in a group of AILD by 48.36 times.
Also, high IL-8 serum levels were strongly related to clinical parameters.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Akberova, Dilyara& Kiassov, Andrey P.& Abdulganieva, Diana. 2017. Serum Cytokine Levels and Their Relation to Clinical Features in Patients with Autoimmune Liver Diseases. Journal of Immunology Research،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182281
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Akberova, Dilyara…[et al.]. Serum Cytokine Levels and Their Relation to Clinical Features in Patients with Autoimmune Liver Diseases. Journal of Immunology Research No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1182281
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Akberova, Dilyara& Kiassov, Andrey P.& Abdulganieva, Diana. Serum Cytokine Levels and Their Relation to Clinical Features in Patients with Autoimmune Liver Diseases. Journal of Immunology Research. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182281
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182281
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر