Total Reflection X-Ray Fluorescence Spectroscopy (TXRF) Method Validation: Determination of Heavy Metals in Dietary Supplements
المؤلفون المشاركون
Beltrán, Blanca G.
Ramos-Sanchez, Victor
Chávez-Flores, David
Rodríguez-Maese, Rogelio
Palacio, Edwin
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-03
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Dietary supplements may contain heavy metals with the property of bioaccumulation in humans.
The aim of this research was to validate and apply two analytical methods to determine Pb, As, Cr, and Hg in dietary supplements by Total Reflection X-ray Fluorescence Spectroscopy (TXRF).
Methods validation was conducted through a multivariate analysis using a central composite design (CCD) and a desirability function.
Critical values for each study variable were established.
The TXRF_DS_1 method was proposed for Pb, As, and Cr determinations, while the TXRF_DS_2 was established for Hg analysis.
The digestion method with an acid mixture (HNO3 + HCl + H2O2) was used to break down the organic material of dietary supplements.
A solution of 10 μg L−1 Ga was used as an internal standard.
Excellent analytical performance was obtained as LODs of 0.59, 0.41, 0.57, and 0.75 μg L−1 and LOQs of 1.95, 1.35, 1.90, and 2.50 μgL −1 for Pb, As, Cr, and Hg, respectively.
Calibration curves showed a good linearity for all elements (R2>0.999).
Excellent accuracy and precision in measurements (% RSD) was achieved.
The real and spiked samples analysis demonstrated the applicability of the TXRF technique (percentage recovery 91–108%).
Besides, two samples were analyzed in a comparison study between the TXRF_DS_1 method and the ICP-OES method.
The results obtained showed good agreement between both techniques.
The TXRF technique allows the analysis of toxic heavy metals in dietary supplements, which are marketed in a wide variety of presentations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Beltrán, Blanca G.& Ramos-Sanchez, Victor& Chávez-Flores, David& Rodríguez-Maese, Rogelio& Palacio, Edwin. 2020. Total Reflection X-Ray Fluorescence Spectroscopy (TXRF) Method Validation: Determination of Heavy Metals in Dietary Supplements. Journal of Chemistry،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1182418
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Beltrán, Blanca G.…[et al.]. Total Reflection X-Ray Fluorescence Spectroscopy (TXRF) Method Validation: Determination of Heavy Metals in Dietary Supplements. Journal of Chemistry No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1182418
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Beltrán, Blanca G.& Ramos-Sanchez, Victor& Chávez-Flores, David& Rodríguez-Maese, Rogelio& Palacio, Edwin. Total Reflection X-Ray Fluorescence Spectroscopy (TXRF) Method Validation: Determination of Heavy Metals in Dietary Supplements. Journal of Chemistry. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1182418
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182418
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر