Biogenetic Conversion of Wyerone and Dihydrowyerone into Wyerone Epoxide in Vicia faba Cotyledons and Screening of Antibacterial Activity
المؤلفون المشاركون
Shakya, Ashok K.
Al-Douri, Nedhal A.
Haddadin, Randa N.
Oriquat, Ghaleb A.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Vicia faba is a plant that belongs to the family Fabaceae.
Cotyledons of this plant produce compounds called phytoalexins as a result of fungal and bacterial infection or stress factors.
The phytoalexins are furanoacetylenic compounds.
They include wyerone, wyerol, wyerone acid, their dihydro derivatives, and wyerone epoxide.
These compounds have antimicrobial activities mainly against fungi.
Objective.
The purpose of this study was to elucidate the biogenetic conversion of wyerone and dihydrowyerone to wyerone epoxide in V.
faba and to investigate the antibacterial activities of some of these phytoalexins.
Materials and Methods.
Seeds of Vicia faba were used.
Labelled wyerone and dihydrowyerone were obtained by treating CuCl2-induced cotyledons with sodium (2-14C) acetate and separated by TLC and HPLC.
Labelled wyerone and dihydrowyerone were then applied to induced bean cotyledons to establish any possible interconversion to wyerone epoxide.
Antibacterial activity of wyerone, wyerone acid, and wyerone epoxide was investigated by disc diffusion test against a panel of microorganisms.
Zones of inhibition were reported.
Results.
The radiolabeling studies showed that 12.4% of 14C-wyerone, and 6.01% of 14C-dihydrowyerone were incorporated into wyerone epoxide.
This indicates that wyerone epoxide was most probably derived from wyerone and dihydrowyerone.
In addition, a new compound, 11-hydroxywyerone was isolated for the first time.
Additionally, this study showed that wyerone, wyerone epoxide, and wyerone acid had no antibacterial activity against Gram-negative bacteria but were active against Gram-positive bacteria.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Al-Douri, Nedhal A.& Haddadin, Randa N.& Shakya, Ashok K.& Oriquat, Ghaleb A.. 2018. Biogenetic Conversion of Wyerone and Dihydrowyerone into Wyerone Epoxide in Vicia faba Cotyledons and Screening of Antibacterial Activity. Journal of Chemistry،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1182549
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Al-Douri, Nedhal A.…[et al.]. Biogenetic Conversion of Wyerone and Dihydrowyerone into Wyerone Epoxide in Vicia faba Cotyledons and Screening of Antibacterial Activity. Journal of Chemistry No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1182549
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Al-Douri, Nedhal A.& Haddadin, Randa N.& Shakya, Ashok K.& Oriquat, Ghaleb A.. Biogenetic Conversion of Wyerone and Dihydrowyerone into Wyerone Epoxide in Vicia faba Cotyledons and Screening of Antibacterial Activity. Journal of Chemistry. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1182549
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182549
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر