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Formulation and Characterization of Hydroquinone Nanostructured Lipid Carriers by Homogenization Emulsification Method
المؤلفون المشاركون
Lin, Chih-Chien
Wu, Pey-Shiuan
Lin, Chih-Hung
Kuo, Yi-Ching
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Nanostructured lipid carrier (NLC) was prepared by homogenization emulsification method and improved with modified surfactants.
The properties of nanoparticles were investigated using the NLC system for hydroquinone (HQ) as a model drug and by increasing the light stability of hydroquinone.
The optimized condition of NLC in stirring was 1200 rpm, the homogenized speed was 8000 rpm, solid oil to liquid oil ratio was 3 : 7, and lecithin to surfactant ratio was 3 : 1.
The particle size was 393.30±28.23 nm and the encapsulation efficiency was 22.13±2.66%.
The zeta-potential of HQ-NLC was better than −30 mV.
In the thermogravimetric analysis (TGA) studies, adding of PLANTACARE 2000 UP for HQ-NLC has better heat resisting property than the HQ-NLC only.
The addition of PLANTACARE 2000 UP to NLC shows better permeability (125.10%) than that of Blank.
In the stability studies, the HQ-NLC after UVA/UVB irradiation has better inhibition rate (34.25%) than that of the Blank.
In the present study, NLC system has successfully improved the light stability and the skin permeability of active compound.
Therefore, the NLC might be a potential delivery vehicle for transdermal products in the future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Pey-Shiuan& Lin, Chih-Hung& Kuo, Yi-Ching& Lin, Chih-Chien. 2017. Formulation and Characterization of Hydroquinone Nanostructured Lipid Carriers by Homogenization Emulsification Method. Journal of Nanomaterials،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182874
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Pey-Shiuan…[et al.]. Formulation and Characterization of Hydroquinone Nanostructured Lipid Carriers by Homogenization Emulsification Method. Journal of Nanomaterials No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1182874
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Pey-Shiuan& Lin, Chih-Hung& Kuo, Yi-Ching& Lin, Chih-Chien. Formulation and Characterization of Hydroquinone Nanostructured Lipid Carriers by Homogenization Emulsification Method. Journal of Nanomaterials. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1182874
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182874
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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