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Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema
المؤلفون المشاركون
Yang, C.-H.
Yang, Chang-Hao
Hsieh, Yi-Ting
Lai, Ivan Pochou
Huang, Wei-Lun
Ho, Tzyy-Chang
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Aims.
To investigate the correlations between renal biomarkers and the treatment outcomes of ranibizumab for diabetic macular edema (DME).
Methods.
This hospital-based study retrospectively enrolled 88 eyes from 67 patients who had received one-year intravitreal ranibizumab treatment for DME.
Best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) at baseline and during the follow-up period were recorded.
BCVA and OCT characteristics at baseline and their changes after ranibizumab treatment were compared between different proteinuria and estimated glomerular filtration rate (eGFR) groups.
Results.
Of the 88 eyes studied, those with moderately increased proteinuria had a thicker central subfield foveal thickness (CFT) and a higher proportion of intraretinal cysts than those with no proteinuria (P=0.012 and 0.045, respectively) at baseline.
After one year of ranibizumab treatment, the reduction in CFT was greater in patients with severely increased proteinuria than those with normal to mildly increased proteinuria (P=0.030).
On the other hand, patients with an eGFR <30 tended to have poorer visual improvements than those with normal eGFR (P=0.044).
Conclusions.
After ranibizumab treatment for DME, patients with severe proteinuria tended to gain better anatomical improvement, while those with poor eGFR tended to have poorer visual improvement.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lai, Ivan Pochou& Huang, Wei-Lun& Yang, C.-H.& Yang, Chang-Hao& Ho, Tzyy-Chang& Hsieh, Yi-Ting. 2020. Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1183352
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lai, Ivan Pochou…[et al.]. Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema. Journal of Diabetes Research No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1183352
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lai, Ivan Pochou& Huang, Wei-Lun& Yang, C.-H.& Yang, Chang-Hao& Ho, Tzyy-Chang& Hsieh, Yi-Ting. Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1183352
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183352
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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