Choroidal Thickness and Ganglion Cell Complex in Pubescent Children with Type 1 Diabetes without Diabetic Retinopathy Analyzed by Spectral Domain Optical Coherence Tomography
المؤلفون المشاركون
Gołębiewska, Joanna
Olechowski, Andrzej
Wysocka-Mincewicz, Marta
Baszyńska-Wilk, Marta
Groszek, Artur
Czeszyk-Piotrowicz, Agnieszka
Szalecki, Mieczysław
Hautz, Wojciech
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-04-03
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Aim.
To assess the retinal and choroidal thickness and ganglion cell complex (GCC) in pubescent children with type 1 diabetes (T1D) without diabetic retinopathy (DR), using spectral domain optical coherence tomography (SD-OCT).
Materials and Method.
Sixty-four right eyes of 64 subjects with T1D and 45 right eyes of 45 age-matched healthy volunteers (control group) were enrolled in this study.
The mean age of the subjects and controls was 15.3 (±SD = 2.2) and 14.6 (±SD = 1.5), respectively.
SD-OCT was performed using RTVue XR Avanti.
Ganglion cell complex (GCC), GCC focal loss volume (FLV), GCC global loss volume (GLV), choroidal thickness (CT), foveal (FT) and parafoveal thickness (PFT), and foveal (FV) and parafoveal volume (PFV) data were analyzed.
Results.
There was no significant difference between subjects and controls in the CT in the fovea and nasal, temporal, superior, and inferior quadrants of the macula.
There were no significant correlations between CT, duration of diabetes, and HbA1C level (p=0.272 and p=0.197, resp.).
GCC thickness did not differ significantly between the groups (p=0.448), but there was a significant difference in FLV (p=0.037).
Significant differences between the groups were found in the PFT and PFV (p=0.004 and p=0.005, resp.).
There was a significant negative correlation between PFT, PFV, and HbA1C level (p=0.002 and p=0.001, resp.).
Conclusions.
Choroidal thickness remains unchanged in children with T1D.
Increased GCC FLV might suggest an early alteration in neuroretinal tissue.
Parafoveal retinal thickness is decreased in pubescent T1D children and correlates with HbA1C level.
OCT can be considered a part of noninvasive screening in children with T1D and a tool for early detection of retinal and choroidal abnormalities.
Further OCT follow-up is needed to determine whether any of the discussed OCT measurements are predictive of future DR severity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gołębiewska, Joanna& Olechowski, Andrzej& Wysocka-Mincewicz, Marta& Baszyńska-Wilk, Marta& Groszek, Artur& Czeszyk-Piotrowicz, Agnieszka…[et al.]. 2018. Choroidal Thickness and Ganglion Cell Complex in Pubescent Children with Type 1 Diabetes without Diabetic Retinopathy Analyzed by Spectral Domain Optical Coherence Tomography. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1183682
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gołębiewska, Joanna…[et al.]. Choroidal Thickness and Ganglion Cell Complex in Pubescent Children with Type 1 Diabetes without Diabetic Retinopathy Analyzed by Spectral Domain Optical Coherence Tomography. Journal of Diabetes Research No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1183682
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gołębiewska, Joanna& Olechowski, Andrzej& Wysocka-Mincewicz, Marta& Baszyńska-Wilk, Marta& Groszek, Artur& Czeszyk-Piotrowicz, Agnieszka…[et al.]. Choroidal Thickness and Ganglion Cell Complex in Pubescent Children with Type 1 Diabetes without Diabetic Retinopathy Analyzed by Spectral Domain Optical Coherence Tomography. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1183682
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183682
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر