Two-Year Changes in Hyperuricemia and Risk of Diabetes: A Five-Year Prospective Cohort Study
المؤلفون المشاركون
Zhao, Zhan
Guo, Xiuhua
Zhang, Jingbo
Tao, Lixin
Liu, Jia
Mu, Yongmin
Zou, Dechun
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Hyperuricemia is known to be a risk factor for diabetes.
However, information is limited regarding the association between changes in hyperuricemia and the risk of diabetes.
Methods.
A total of 15,403 participants who were free of diabetes at the time of 2009 and 2011 surveys in the Beijing Health Management Cohort (BHMC) study were recruited and followed up until 2016.
Participants were classified into four groups according to 2-year changes in hyperuricemia: no hyperuricemia, remittent hyperuricemia, incident hyperuricemia, and persistent hyperuricemia.
Modified Poisson regression models were used to evaluate the effect of 2-year changes in hyperuricemia on the risk of diabetes.
Results.
During the 5-year follow-up, we identified 841 new cases of diabetes (216 women).
Remittent hyperuricemia and incident hyperuricemia had a 35% and 48% higher risk for developing diabetes compared with no hyperuricemia.
Especially, persistent hyperuricemia was associated with a 75% higher risk of diabetes (RR = 1.75, 95% CI = 1.47-2.08).
Compared with minor serum uric acid (SUA) change, over 10% decline and over 30% increase in SUA levels were subsequently associated with lower (RR = 0.84, 95% CI = 0.72-0.99) and higher (RR = 1.71, 95% CI = 1.27-2.30) diabetes risk, respectively.
Conclusions.
Changes in hyperuricemia, especially persistent hyperuricemia, are more appropriate to reflect the risk of diabetes than a single measurement of hyperuricemia at baseline.
Strategies aiming at preventing hyperuricemia are urgently needed to reduce the increasing burden of diabetes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Jia& Tao, Lixin& Zhao, Zhan& Mu, Yongmin& Zou, Dechun& Zhang, Jingbo…[et al.]. 2018. Two-Year Changes in Hyperuricemia and Risk of Diabetes: A Five-Year Prospective Cohort Study. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1183814
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Jia…[et al.]. Two-Year Changes in Hyperuricemia and Risk of Diabetes: A Five-Year Prospective Cohort Study. Journal of Diabetes Research No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1183814
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Jia& Tao, Lixin& Zhao, Zhan& Mu, Yongmin& Zou, Dechun& Zhang, Jingbo…[et al.]. Two-Year Changes in Hyperuricemia and Risk of Diabetes: A Five-Year Prospective Cohort Study. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1183814
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183814
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر