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Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications
المؤلفون المشاركون
Yimer, Ebrahim M.
Zewdie, Kaleab Alemayehu
Hishe, Hailemichael Zeru
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-20، 20ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-09-18
دولة النشر
مصر
عدد الصفحات
20
التخصصات الرئيسية
الملخص EN
Diabetes is a multifactorial metabolic syndrome and is one of the shared long-lasting illnesses globally.
It is linked to long-term microvascular and macrovascular complications that contribute to disability, compromised quality of life, and reduction in lifespan, which eventually leads to death.
This disease is not only incurring significant economic burden but also adversely affects the patients, caregivers, communities, and the society at large.
The interruption of diabetes progress and its complications is a primary focus of scientific communities.
In spite of various diagnostic modalities for diabetes, there is a limited marker to investigate the risk and progress of its complications.
Netrin has recently received more attention as a biomarker of diabetes and a broader range of long-term complication.
Therefore, the impetus of this review is to exhaustively discuss the role of Netrin as a potential biomarker and its therapeutic implication in diabetes and diverse sets of microvascular and macrovascular complications of diabetes.
It also discourses the possible mechanisms of Netrin for the said pharmacological effect for a better understanding of the development and progression of diabetes and its complications in relation to this protein.
It enables protective measures to be applied at the subclinical stage and the responses to preventive or therapeutic measures to be scrutinized.
Besides, it might also facilitate the appraisal of novel therapeutic options for diabetes and various complications through modifying the endogenous Netrin and provide surrogate endpoints for intervention.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yimer, Ebrahim M.& Zewdie, Kaleab Alemayehu& Hishe, Hailemichael Zeru. 2018. Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications. Journal of Diabetes Research،Vol. 2018, no. 2018, pp.1-20.
https://search.emarefa.net/detail/BIM-1183947
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yimer, Ebrahim M.…[et al.]. Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications. Journal of Diabetes Research No. 2018 (2018), pp.1-20.
https://search.emarefa.net/detail/BIM-1183947
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yimer, Ebrahim M.& Zewdie, Kaleab Alemayehu& Hishe, Hailemichael Zeru. Netrin as a Novel Biomarker and Its Therapeutic Implications in Diabetes Mellitus and Diabetes-Associated Complications. Journal of Diabetes Research. 2018. Vol. 2018, no. 2018, pp.1-20.
https://search.emarefa.net/detail/BIM-1183947
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1183947
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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