Evaluation of Angiopoietins 1 and 2 in Malaria-Infested Children
المؤلفون المشاركون
Oluboyo, A. O.
Chukwu, S. I.
Oluboyo, B. O.
Odewusi, O. O.
المصدر
Journal of Environmental and Public Health
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-26
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Malaria could affect people of all ages, most especially young children.
The study evaluated the levels of serum angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) which are critical regulators of endothelial activation and integrity with some hematological parameters (total white blood cell counts (WBC), total red blood cell counts (RBC), platelet counts, and malaria parasite density) in malaria-infected children.
Method.
A total of 92 blood samples from children between the ages of 6 months to 15 years were analyzed.
The samples consisted of 30 cases of severe malaria, 40 cases of uncomplicated malaria, and 22 apparently healthy subjects served as control.
Serum Ang-1 and -2 levels were determined using the enzyme-linked immunosorbent assay technique.
The hematological parameters were determined using the WHO standard.
Results.
There was significant decrease (p<0.05) in serum Ang-1 of uncomplicated malaria and severe malaria compared with the control, while significant increase (p<0.05) was observed in Ang-2 and Ang-2/Ang-1 ratio in uncomplicated malaria and severe malaria compared with the control.
RBC and platelet showed significant decrease, while WBC showed significant increase in severe malaria compared with uncomplicated malaria and control.
Conclusion.
This study showed that subjects with malaria infection had a significant increase of Ang-2 and Ang-2 : Ang-1 ratio but presented with a significant decrease of Ang-1.
Ang-1 and Ang-2 may be used to determine the severity of malaria infection since their levels differ significantly in malaria subjects compared with the control.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oluboyo, A. O.& Chukwu, S. I.& Oluboyo, B. O.& Odewusi, O. O.. 2020. Evaluation of Angiopoietins 1 and 2 in Malaria-Infested Children. Journal of Environmental and Public Health،Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1184212
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oluboyo, A. O.…[et al.]. Evaluation of Angiopoietins 1 and 2 in Malaria-Infested Children. Journal of Environmental and Public Health No. 2020 (2020), pp.1-5.
https://search.emarefa.net/detail/BIM-1184212
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oluboyo, A. O.& Chukwu, S. I.& Oluboyo, B. O.& Odewusi, O. O.. Evaluation of Angiopoietins 1 and 2 in Malaria-Infested Children. Journal of Environmental and Public Health. 2020. Vol. 2020, no. 2020, pp.1-5.
https://search.emarefa.net/detail/BIM-1184212
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1184212
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر