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Long-Term Effects of Environmental Lead Exposure on Blood Pressure and Plasma Soluble Cell Adhesion Molecules in Young Adults: A Follow-Up Study of a Prospective Cohort in Kosovo
المؤلفون المشاركون
Camaj, Pashko R.
Graziano, Joseph H.
Preteni, Emine
Popovac, Dusan
LoIacono, Nancy
Balac, Olgica
Factor-Litvak, Pam R.
المصدر
Journal of Environmental and Public Health
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-08
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background and Aims.
Epidemiologic studies examining the relationship between environmental lead (Pb) exposure and blood pressure (BP) generally report small associations between blood lead concentration (BPb) and BP.
However, these studies are predominantly cross-sectional.
In addition, no epidemiologic studies evaluate associations between either current or past Pb exposure and serum levels of markers of systemic inflammation and endothelial dysfunction, including soluble vascular adhesion molecule (sVCAM-1) and soluble intercellular cell adhesion molecule (sICAM-1).
We prospectively investigate these associations later in life.
Methods.
From our original prospective birth cohort study in Mitrovica (a mining town) and Prishtina (a control town), Kosovo, from 1985 to 1998, we located and assessed BPb and BP in 101 participants (mean age of 24.9 years old) in 2011.
Results.
We found highly statistically significant association between concurrent BPb and sVCAM-1 in men and a marginally significant association between concurrent PBb and sICAM.-1 in women.
We did not find evidence of mediation.
Conclusion.
Current study results, along with previously reported findings on this cohort, provide evidence for the hypothesis that exposure to Pb leads to small increases in sBP and perhaps to increased circulating levels of sVCAM-1 and sICAM-1 later in life.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Camaj, Pashko R.& Graziano, Joseph H.& Preteni, Emine& Popovac, Dusan& LoIacono, Nancy& Balac, Olgica…[et al.]. 2018. Long-Term Effects of Environmental Lead Exposure on Blood Pressure and Plasma Soluble Cell Adhesion Molecules in Young Adults: A Follow-Up Study of a Prospective Cohort in Kosovo. Journal of Environmental and Public Health،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1184769
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Camaj, Pashko R.…[et al.]. Long-Term Effects of Environmental Lead Exposure on Blood Pressure and Plasma Soluble Cell Adhesion Molecules in Young Adults: A Follow-Up Study of a Prospective Cohort in Kosovo. Journal of Environmental and Public Health No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1184769
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Camaj, Pashko R.& Graziano, Joseph H.& Preteni, Emine& Popovac, Dusan& LoIacono, Nancy& Balac, Olgica…[et al.]. Long-Term Effects of Environmental Lead Exposure on Blood Pressure and Plasma Soluble Cell Adhesion Molecules in Young Adults: A Follow-Up Study of a Prospective Cohort in Kosovo. Journal of Environmental and Public Health. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1184769
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1184769
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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