Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects
المؤلفون المشاركون
Farup, Per G.
Lydersen, Stian
Valeur, Jørgen
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Obesity has been associated with changes in the gut microbiota and its metabolites.
The study explored changes in the faecal microbiota and short-chain fatty acids (SCFA) associated with the diet (including nonnutritive sweeteners (NNSs)) and evaluated metabolic consequences in subjects with morbid obesity.
The diet was assessed with a validated food frequency questionnaire.
One unit of NNSs was 100 mL beverage with NNSs or 2 tablets/teaspoons of NNSs.
The faecal microbiota was assessed with GA-map® dysbiosis test and SCFA with gas chromatography and flame ionisation detection.
Fourteen men and 75 women with a mean age of 44.6 (SD 8.7) years, BMI 41.8 (SD 3.6) kg/m2, and intake of NNSs 7.5 units/day (SD 3.2; range 0–43) were included.
Faecal butyric acid was positively and negatively associated with the intake of starch (partial correlation = 0.264; p=0.015) and NNSs (partial correlation = −0.274; p=0.011), respectively.
NNSs were associated with changes in four out of 39 bacterial groups.
Butyric acid has antiobesogenic effects, reduces insulin resistance, and improves dyslipidaemia.
Since the weight-reducing effect of NNSs on obese adults trying to lose weight is dubious, it seems imprudent to use NNSs that might counteract the favourable effects of butyric acid.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farup, Per G.& Lydersen, Stian& Valeur, Jørgen. 2019. Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects. Journal of Obesity،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1184869
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farup, Per G.…[et al.]. Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects. Journal of Obesity No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1184869
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farup, Per G.& Lydersen, Stian& Valeur, Jørgen. Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects. Journal of Obesity. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1184869
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1184869
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر