Comparison of Intravitreal Aflibercept and Ranibizumab for Treatment of Myopic Choroidal Neovascularization: One-Year Results—A Retrospective, Comparative Study

المؤلفون المشاركون

Cakir, Akin
Erden, Burak
Bolukbasi, Selim
Baş, Emine

المصدر

Journal of Ophthalmology

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-10-31

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

Purpose.

To compare one-year treatment outcomes of intravitreal aflibercept (IVA) and intravitreal ranibizumab (IVR) for treatment of myopic choroidal neovascularization (mCNV).

Methods.

The medical records of a total of 30 eyes diagnosed with mCNV and underwent IVA or IVR treatment for a minimum one-year follow-up were studied retrospectively.

All the subjects had an axial length >26 mm and received a 1 + PRN (pro re nata) regimen IVA or IVR.

Best-corrected visual acuity (BCVA) and central macular thicknesses (CMT) on optical coherence tomography were evaluated before and after treatment.

Results.

There were 12 eyes in IVA group, with a mean age of 60.0 ± 10.2 years.

The mean BCVA significantly improved from baseline 1.54 ± 0.76 to 0.85 ± 0.61 and the mean CMT significantly decreased from baseline 384.3 ± 119.1 μm to 305.9 ± 75.4 μm at Month 12 (p:0.024 and p:0.011, respectively).

There were 18 eyes in IVR group, with a mean age of 57.4 ± 13.1 years.

The mean BCVA improved from baseline 1.14 ± 0.90 to 1.04 ± 0.93 and the mean CMT significantly decreased from baseline 366.5 ± 102.3 μm to 323.6 ± 103.6 μm at Month 12 after IVR (p:0.345 and p:0.011, respectively).

There was no significant difference between the groups in CMT changes in the study period (p:0.178), but IVA resulted in significantly better final visual gain (0.69 versus 0.09; p:0.006).

Conclusions.

Both IVA and IVR treatment modalities resulted in similar anatomical outcomes but IVA had better visual outcomes in treatment of mCNV.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Erden, Burak& Bolukbasi, Selim& Baş, Emine& Cakir, Akin. 2019. Comparison of Intravitreal Aflibercept and Ranibizumab for Treatment of Myopic Choroidal Neovascularization: One-Year Results—A Retrospective, Comparative Study. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1186313

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Erden, Burak…[et al.]. Comparison of Intravitreal Aflibercept and Ranibizumab for Treatment of Myopic Choroidal Neovascularization: One-Year Results—A Retrospective, Comparative Study. Journal of Ophthalmology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1186313

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Erden, Burak& Bolukbasi, Selim& Baş, Emine& Cakir, Akin. Comparison of Intravitreal Aflibercept and Ranibizumab for Treatment of Myopic Choroidal Neovascularization: One-Year Results—A Retrospective, Comparative Study. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1186313

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1186313