Early Alterations of Corneal Subbasal Plexus in Uncomplicated Type 1 Diabetes Patients
المؤلفون المشاركون
Schiano-Lomoriello, Domenico
Picconi, Fabiana
Frontoni, Simona
Parravano, Mariacristina
Giannini, Daniela
Russo, Benedetta
Abicca, Irene
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
The purpose of our study is to describe the in vivo corneal confocal microscopy characteristics of subbasal nerve plexus in a highly selected population of patients affected by type 1 diabetes mellitus (T1DM) without any microvascular diabetes complications.
Methods.
We included 19 T1DM patients without diabetic peripheral neuropathy, diabetic autonomic neuropathy, diabetic retinopathy, and microalbuminuria.
All patients underwent in vivo corneal confocal microscopy and blood analysis to determine subbasal nerve plexus parameters and their correlation with clinical data.
We compared the results with 19 healthy controls.
Results.
The T1DM group showed a significant decrease of the nerve fiber length (P=0.032), the nerve fiber length density (P=0.034), the number of fibers (P=0.005), and the number of branchings (P=0.028), compared to healthy subjects.
The nerve fiber length, nerve fiber length density, and number of fibers were directly related to the age at onset of diabetes and inversely to the duration of DM.
BMI (body mass index) was highly related to the nerve fiber length (r = −0.6, P=0.007), to the nerve fiber length density (r = −0.6, P=0.007), and to the number of fibers (r = −0.587, P=0.008).
No significant correlations were found between the corneal parameters and HbA1c.
Conclusions.
Early subclinical fiber corneal variation could be easily detected using in vivo corneal confocal microscopy, even in type 1 diabetes without any microvascular diabetes complications, including diabetic peripheral neuropathy, diabetic autonomic neuropathy, diabetic retinopathy, and microalbuminuria.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Schiano-Lomoriello, Domenico& Abicca, Irene& Parravano, Mariacristina& Giannini, Daniela& Russo, Benedetta& Frontoni, Simona…[et al.]. 2019. Early Alterations of Corneal Subbasal Plexus in Uncomplicated Type 1 Diabetes Patients. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186518
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Schiano-Lomoriello, Domenico…[et al.]. Early Alterations of Corneal Subbasal Plexus in Uncomplicated Type 1 Diabetes Patients. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1186518
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Schiano-Lomoriello, Domenico& Abicca, Irene& Parravano, Mariacristina& Giannini, Daniela& Russo, Benedetta& Frontoni, Simona…[et al.]. Early Alterations of Corneal Subbasal Plexus in Uncomplicated Type 1 Diabetes Patients. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1186518
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1186518
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر