Clinical Characteristics of Systemic Lupus Erythematosus with Cirrhosis
المؤلفون المشاركون
Zhang, Wen
Li, Mengtao
Zhao, Jiuliang
Zeng, Xiaofeng
Wang, Qian
Peng, Linyi
You, Hanxiao
Fei, Yunyun
المصدر
Journal of Immunology Research
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-21
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aim.
Cirrhosis is rare in systemic lupus erythematosus (SLE) patients with a poor prognosis.
This study is aimed at retrospectively analyzing our single-center experience to explore the characteristics of cirrhosis in SLE patients.
Methods.
SLE patients with cirrhosis from 2012 to 2019 were enrolled.
SLE diagnosis was rigorously confirmed by a medical record review according to the revised 1997 American College of Rheumatology classification criteria for SLE.
The diagnosis of liver cirrhosis was based on a combination of clinical, laboratory, and imaging criteria features.
We conducted a case-control study in SLE patients complicated with the cirrhosis group and the age-, sex-, and entry-time-matched noncirrhosis group.
Results.
A total of 21 patients with SLE cirrhosis were enrolled, 3 males and 18 females.
The median age at the time of cirrhosis diagnosis was 47.3±4.0 years, and the mean disease duration of SLE before cirrhosis was 4.7±1.0 years.
The most common initial presentation was the involvement of the hematological system in 9 patients and then skin and mucosal involvement in 5 patients, arthritis in 4 patients, and nephritis in 3 patients.
Patients with cirrhosis had a significantly higher rate of hematological system involvement (thrombocytopenia and leukopenia) and worse liver function; a higher level of immune globulin G had higher mortality (p<0.05) than patients without cirrhosis.
Conclusions.
Cirrhosis is a rare and severe subtype of SLE with a poor prognosis.
Those patients with hematological system involvement and impaired liver function should be paid more attention.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
You, Hanxiao& Peng, Linyi& Zhao, Jiuliang& Fei, Yunyun& Wang, Qian& Zhang, Wen…[et al.]. 2020. Clinical Characteristics of Systemic Lupus Erythematosus with Cirrhosis. Journal of Immunology Research،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1186990
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
You, Hanxiao…[et al.]. Clinical Characteristics of Systemic Lupus Erythematosus with Cirrhosis. Journal of Immunology Research No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1186990
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
You, Hanxiao& Peng, Linyi& Zhao, Jiuliang& Fei, Yunyun& Wang, Qian& Zhang, Wen…[et al.]. Clinical Characteristics of Systemic Lupus Erythematosus with Cirrhosis. Journal of Immunology Research. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1186990
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1186990
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر