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Profiling the Resident and Infiltrating MonocyteMacrophages during Rejection following Kidney Transplantation
المؤلفون المشاركون
Huang, Yuming
Zhao, Jingjie
Huang, Peng
Luo, Peiling
Tan, Junhua
Huang, Feifan
Ma, Ruiying
Huang, Meiying
Wei, Qiuju
Wei, Liuzhi
Wang, Zechen
Meng, Lingzhang
Wang, Jie
المصدر
Journal of Immunology Research
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-21
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Immune tolerance research is essential for kidney transplantation.
Other than antibody and T cell-mediated immune rejection, macrophage-mediated innate immunity plays an important role in the onset phase of transplantation rejection.
However, due to the complexity of the kidney environment as well as its diversity and low abundance, studies pertaining to monocyte/macrophages in kidney transplantation require further elucidation.
In this study, kidney samples taken from healthy human adults and biopsy specimens from patients undergoing rejection following kidney transplantation were analysed and studied.
By conducting a single-cell RNA analysis, the type and status of monocyte/macrophages in kidney transplantation were described, in which monocyte/macrophages were observed to form two different subpopulations: resident and infiltrating monocyte/macrophages.
Furthermore, previously defined genes were mapped to all monocyte/macrophage types in the kidney and enriched the differential genes of the two main subpopulations using gene expression databases.
Considering that various cases of rejection may be of the monocyte/macrophage type, the present data may serve as a reference for studies regarding immune tolerance following kidney transplantation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Jie& Luo, Peiling& Zhao, Jingjie& Tan, Junhua& Huang, Feifan& Ma, Ruiying…[et al.]. 2020. Profiling the Resident and Infiltrating MonocyteMacrophages during Rejection following Kidney Transplantation. Journal of Immunology Research،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1187320
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Jie…[et al.]. Profiling the Resident and Infiltrating MonocyteMacrophages during Rejection following Kidney Transplantation. Journal of Immunology Research No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1187320
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Jie& Luo, Peiling& Zhao, Jingjie& Tan, Junhua& Huang, Feifan& Ma, Ruiying…[et al.]. Profiling the Resident and Infiltrating MonocyteMacrophages during Rejection following Kidney Transplantation. Journal of Immunology Research. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1187320
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1187320
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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