Is there a Role of Intravenous Immunoglobulin in Immunologic Recurrent Pregnancy Loss?
المؤلفون المشاركون
المصدر
Journal of Immunology Research
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-28
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Recurrent pregnancy loss (RPL) commonly refers to three or more miscarriages that occur before 20 weeks of pregnancy.
The immunological cause of RPL could be either an auto- or alloimmune-related event or both.
Because of the discovery of immunological abnormalities in RPL patients in clinical practice, several immunomodulatory therapies were introduced to maintain the immune balance at the maternal-fetal interface.
Intravenous immunoglobulin (IVIg) is one of the immunomodulators.
In recent years, several studies have analyzed the therapeutic effect of IVIg on RPL patients with antiphospholipid syndrome (APS) or unexplained RPL.
However, their results are controversial.
IVIg can be used in RPL patients with APS who have previously failed in other treatments.
It is recommended that IVIg infusion could be considered used before conception in RPL patients who have cellular immune abnormalities such as increased natural killer (NK) cell counts, NK cell cytotoxicity, or increased T helper (Th)1/Th2 ratio, depending on the cut-off values of each hospital.
The aim of this review was to summarize the mechanisms, efficacy, pharmacokinetics, and side effects associated with passive immunization using IVIg in immunologic RPL, according to the literature published in recent years.
We hope that more obstetricians will be able to understand the timing and indication of IVIg properly in immunologic RPL patients and effectively enhance pregnancy outcomes for mothers and neonates.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Xiuhua& Meng, Tao. 2020. Is there a Role of Intravenous Immunoglobulin in Immunologic Recurrent Pregnancy Loss?. Journal of Immunology Research،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1187393
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Xiuhua& Meng, Tao. Is there a Role of Intravenous Immunoglobulin in Immunologic Recurrent Pregnancy Loss?. Journal of Immunology Research No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1187393
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Xiuhua& Meng, Tao. Is there a Role of Intravenous Immunoglobulin in Immunologic Recurrent Pregnancy Loss?. Journal of Immunology Research. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1187393
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1187393
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر