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Continuous Aspiration Thrombectomy in High- and Intermediate-High-Risk Pulmonary Embolism in Real-World Clinical Practice
المؤلفون المشاركون
Krasiński, Zbigniew
Araszkiewicz, Aleksander
Sławek-Szmyt, Sylwia
Jankiewicz, Stanisław
Żabicki, Bartosz
Grygier, Marek
Mularek-Kubzdela, Tatiana
Lesiak, Maciej
المصدر
Journal of Interventional Cardiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-21
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objectives.
We sought to assess the technical and clinical feasibility of continuous aspiration catheter-directed mechanical thrombectomy (CDT) in patients with high- or intermediate-high-risk pulmonary embolism (PE).
Methods and Results.
Fourteen patients (eight women and six men; age range: 29–71 years) with high- or intermediate-high-risk PE and contraindications to or ineffective systemic thrombolysis were prospectively enrolled between October 2018 and February 2020.
The Indigo Mechanical Thrombectomy System (Penumbra, Inc., Alameda, California) was used as CDT device.
Low-dose local thrombolysis (alteplase, 3–12 mg) was additionally applied in three patients.
Technical and procedural success was achieved in 14 patients (100%).
Complete or nearly complete clearance of pulmonary arteries was achieved in nine patients (64.3%), whereas partial clearance was achieved in five (35.7%).
A significant improvement in the pre- and postprocedural patients’ clinical status was observed in the following fields (median; interquartile range): heart rate (110; 100–120/min vs.
85; 80–90/min; p<0.0001), systolic blood pressure (106; 90–127 mmHg vs.
123; 110–133 mmHg; p=0.049), arterial oxygen saturation (88.5; 84.2–93% vs.
95.0; 93.8–95%, p=0.0051), pulmonary artery systolic pressure (55; 44–66 mmHg vs.
42; 34–53 mmHg; p=0.0015), Miller index score (21.5; 20–23 vs.
9.5; 8–13; p<0.0001) and right ventricular/left ventricular ratio (1.3; 1.3–1.5 vs.
1.0; 0.9–1.0; p<0.0001).
No major periprocedural bleeding was detected.
Conclusions.
CDT is a feasible and promising technique for management of high- or intermediate-high-risk PE to decrease thrombus burden, reduce right heart strain, and improve hemodynamic and clinical status.
Some patients may benefit from simultaneous local low-dose thrombolytic therapy.
Nevertheless, its criteria and role in CTD-managed patients require further elucidation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Araszkiewicz, Aleksander& Sławek-Szmyt, Sylwia& Jankiewicz, Stanisław& Żabicki, Bartosz& Grygier, Marek& Mularek-Kubzdela, Tatiana…[et al.]. 2020. Continuous Aspiration Thrombectomy in High- and Intermediate-High-Risk Pulmonary Embolism in Real-World Clinical Practice. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1187775
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Araszkiewicz, Aleksander…[et al.]. Continuous Aspiration Thrombectomy in High- and Intermediate-High-Risk Pulmonary Embolism in Real-World Clinical Practice. Journal of Interventional Cardiology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1187775
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Araszkiewicz, Aleksander& Sławek-Szmyt, Sylwia& Jankiewicz, Stanisław& Żabicki, Bartosz& Grygier, Marek& Mularek-Kubzdela, Tatiana…[et al.]. Continuous Aspiration Thrombectomy in High- and Intermediate-High-Risk Pulmonary Embolism in Real-World Clinical Practice. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1187775
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1187775
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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