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Index of Microcirculatory Resistance Measured during Intracoronary Adenosine-Induced Hyperemia
المؤلفون المشاركون
Witt, Nils
Santos-Pardo, Irene
Alström, Patrik
المصدر
Journal of Interventional Cardiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-13
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
The index of microcirculatory resistance is an invasive measure of coronary microvascular function that has to be calculated during maximal hyperemia, classically achieved with intravenous adenosine (IV).
The aim of this study was to evaluate the use of intracoronary (IC) adenosine for the calculation of IMR.
Methods and Results.
31 patients with stable coronary artery disease were included in the study.
Coronary pressure and thermodilution measurements were obtained at rest and during maximal hyperemia using a pressure-temperature sensor-tipped coronary guidewire.
Duplicate measurements were performed using first IC and then IV adenosine.
Dispersion of transit times was comparable for IC and IV adenosine.
IMR values based on IC vs IV adenosine showed a high level of agreement and an intraclass correlation coefficient of 0.90.
Applying an upper normal limit of 25, misclassification of IMR using IC adenosine was seen in just one patient in whom IC adenosine resulted in a lower value.
A simplified procedure based on a single bolus dose of saline did not change the level of agreement or the rate of misclassification.
Conclusions.
We found an excellent agreement between IMR values measured during hyperemia induced by IC as compared to IV adenosine.
The use of IC adenosine may facilitate invasive assessment of microvascular function and is potentially time- and cost-saving with less patient discomfort as compared to IV infusion.
The trail is registered with NCT03369184.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Santos-Pardo, Irene& Alström, Patrik& Witt, Nils. 2020. Index of Microcirculatory Resistance Measured during Intracoronary Adenosine-Induced Hyperemia. Journal of Interventional Cardiology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1187803
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Santos-Pardo, Irene…[et al.]. Index of Microcirculatory Resistance Measured during Intracoronary Adenosine-Induced Hyperemia. Journal of Interventional Cardiology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1187803
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Santos-Pardo, Irene& Alström, Patrik& Witt, Nils. Index of Microcirculatory Resistance Measured during Intracoronary Adenosine-Induced Hyperemia. Journal of Interventional Cardiology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1187803
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1187803
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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