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Hip Osteonecrosis Is Associated with Increased Plasma IL-33 Level
المؤلفون المشاركون
Guo, Wanshou
Wang, Bailiang
Ma, Jinhui
Li, Zirong
Li, Shirui
Wang, Peng
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-11
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The recently discovered IL-33 as an IL-1 cytokine family member has been proved to be specifically released from osteonecrotic bones.
We aimed to investigate the potential role of IL-33 in the development of osteonecrosis of femoral head (ONFH).
Forty patients diagnosed with ONFH and forty age-, sex-, and body mass index- (BMI-) matched healthy subjects were included in this prospective study between March 2016 and September 2016.
A commercially available ELISA kit was used to test the level of plasma IL-33.
The IL-33 levels were compared among different ARCO stages, CJFH types, and etiology groups.
Plasma IL-33 levels were significantly higher in the ONFH patients than that in the control subjects.
The levels of IL-33 did not differ significantly among the ONFH patients with different ARCO stages.
The IL-33 levels of patients with CJFH type L3 were significantly higher than that of patients with types L1 and L2.
No significant differences were observed in IL-33 levels between steroid-induced, alcohol-induced, and idiopathic patients.
Our findings seem to indicate that IL-33 effects may be detrimental during ONFH, which appeared to be associated with the prognosis of ONFH.
The IL-33 deserves particular attention in the pathogenesis of ONFH.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ma, Jinhui& Guo, Wanshou& Li, Zirong& Wang, Bailiang& Li, Shirui& Wang, Peng. 2017. Hip Osteonecrosis Is Associated with Increased Plasma IL-33 Level. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1188117
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ma, Jinhui…[et al.]. Hip Osteonecrosis Is Associated with Increased Plasma IL-33 Level. Mediators of Inflammation No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1188117
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ma, Jinhui& Guo, Wanshou& Li, Zirong& Wang, Bailiang& Li, Shirui& Wang, Peng. Hip Osteonecrosis Is Associated with Increased Plasma IL-33 Level. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1188117
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1188117
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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