Vitamin D Deficiency Is Associated with Increased Osteocalcin Levels in Acute Aortic Dissection: A Pilot Study on Elderly Patients
المؤلفون المشاركون
Corsi Romanelli, Massimiliano M.
Vianello, Elena
Lamont, John
Tacchini, Lorenza
Trimarchi, Santi
Marrocco-Trischitta, Massimiliano M.
Barassi, A.
Dozio, Elena
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
An imbalance between degradation and reconstruction of the aortic wall is one of the leading causes of acute aortic dissection (AAD).
Vitamin D seems an intriguing molecule to explore in the field of AAD since it improves endothelial function and protects smooth muscle cells from inflammation-induced remodeling, calcification, and loss of function, all events which are strongly related to the aging process.
We quantified 25-hydroxy vitamin D, calcium, parathormone, bone alkaline phosphatase, and osteocalcin levels in 24 elderly AAD patients to identify a potential pathological implication of these molecules in AAD.
Median 25-hydroxy vitamin D (10.75 ng/mL, 25th–75th percentiles: 6.86–19.23 ng/mL) and calcium levels (8.70 mg/dL, 25th–75th percentiles: 7.30–8.80 mg/dL) suggested hypovitaminosis D and a moderate hypocalcemia.
Thirty-eight percent of AAD patients had severe (<10 ng/mL), 38% moderate (10–20 ng/mL), and 24% mild 25-hydroxy vitamin D deficiency (20–30 ng/mL).
A significant inverse correlation was observed between 25OHD and osteocalcin levels.
All the other molecules were unchanged.
A condition of hypovitaminosis D associated to an increase in osteocalcin levels is present in AAD patients.
The identification of these molecules as new factors involved in AAD may be helpful to identify individuals at high risk as well to study preventing strategies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vianello, Elena& Dozio, Elena& Barassi, A.& Tacchini, Lorenza& Lamont, John& Trimarchi, Santi…[et al.]. 2017. Vitamin D Deficiency Is Associated with Increased Osteocalcin Levels in Acute Aortic Dissection: A Pilot Study on Elderly Patients. Mediators of Inflammation،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1188546
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vianello, Elena…[et al.]. Vitamin D Deficiency Is Associated with Increased Osteocalcin Levels in Acute Aortic Dissection: A Pilot Study on Elderly Patients. Mediators of Inflammation No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1188546
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vianello, Elena& Dozio, Elena& Barassi, A.& Tacchini, Lorenza& Lamont, John& Trimarchi, Santi…[et al.]. Vitamin D Deficiency Is Associated with Increased Osteocalcin Levels in Acute Aortic Dissection: A Pilot Study on Elderly Patients. Mediators of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1188546
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1188546
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر