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Clinicopathological and Prognostic Value of Gastric Carcinoma Highly Expressed Transcript 1 in Cancer: A Meta-Analysis
المؤلفون المشاركون
Zhou, Xi
He, Yu
Fan, Yanghua
Mou, Anna
Wang, Fu
Liu, Yong
Wu, Zhen
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-26
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Background.
Long noncoding RNA gastric cancer highly expressed transcript 1 (lncRNA GHET1) is often reported to be abnormally expressed in multiple cancers, but the situation is different in different cancers.
Therefore, a meta-analysis is necessary to clarify the value of lncRNA GHET1 as a prognostic indicator in cancer.
Methods.
Relevant research studies on lncRNA GHET1 and cancer were retrieved from three electronic literature databases of Web of Science, PubMed, and OVID.
Meanwhile, hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated to explore the relationship between lncRNA GHET1 expression and survival of cancer patients.
The odds ratios (ORs) and 95% CIs were calculated to assess the association of lncRNA GHET1 expression with pathological parameters of cancer patients.
Results.
The meta-analysis included a total of 11 studies involving 714 cancer patients.
The pooled HR suggests that high lncRNA GHET1 expression is associated with poor overall survival.
In addition, high expression of lncRNA GHET1 was found to be associated with larger tumor size, poor histological grade, high tumor stage, lymph node metastasis, and distant metastasis.
Conclusions.
High lncRNA GHET1 expression can predict poor survival and pathological parameters.
And lncRNA GHET1 could serve as a new indicator in multiple cancers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Xi& Fan, Yanghua& He, Yu& Mou, Anna& Wang, Fu& Liu, Yong…[et al.]. 2020. Clinicopathological and Prognostic Value of Gastric Carcinoma Highly Expressed Transcript 1 in Cancer: A Meta-Analysis. Journal of Oncology،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1189023
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Xi…[et al.]. Clinicopathological and Prognostic Value of Gastric Carcinoma Highly Expressed Transcript 1 in Cancer: A Meta-Analysis. Journal of Oncology No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1189023
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Xi& Fan, Yanghua& He, Yu& Mou, Anna& Wang, Fu& Liu, Yong…[et al.]. Clinicopathological and Prognostic Value of Gastric Carcinoma Highly Expressed Transcript 1 in Cancer: A Meta-Analysis. Journal of Oncology. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1189023
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1189023
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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